Active Ingredient History

NOW
  • Now
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Insulin lowers blood glucose levels by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis in adipocytes, inhibits proteolysis, and enhances protein synthesis. Human insulin begins to exert its effects within 30 minutes of subcutaneous administration, while peak levels occur 3-4 hours after administration. Due to its quick onset of action, human insulin is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the pancreas after meals. Bolus insulin is often combined with once daily, long-acting "basal insulin" to provide low concentrations of background insulin that can keep blood sugar stable between meals or overnight. Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin, with a goal of avoiding any periods of hypoglycemia.   NCATS

  • Mechanisms of Action:
  • Multi-specific: No
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.5770 - $285.6600

Australia

$14.5834 - $25.1740
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( insulin human (humulin), insulin lispro (humalog) - other names: humalog mix, humalog mix 50/50 kwikpen, humalog mix 50/50 pen, humalog mix 75/25 pen, novolog mix, novolog mix 70/30 flexpen, novolog mix 70/30 penfill )
actrapid insulin | basal insulin | biod-125 | biod-531 | biphasic human insulin | cp-464,005 | crystalline (aqueous suspension) | exubera | gik | glucose-insulin-potassium | glucose potassium insulin | high molecular weight insulin human | hm12460a | hoe21ph | human insulin | human insulin (rdna) | human recombinant insulin | humulin | humulin br | humulin l | humulin n | humulin r | humulin r pen | humulin s | humulin u | iletin i | iletin ii | ins hum insulat | ins hum protaphane | ins humulin i | ins humulin r | ins humulin zn | ins innolet insulat | ins insulat | ins insulat novolet | ins insuman basal | ins insuman basal optiset | ins insuman basal solostar | ins novolet hum protaphane | ins pur-in hum isop | insulatard nph human | insulin | insulin, 8a-l-threonine-10a-l-isoleucine- | insulin human | insulin (human) | insulin, human | insulin human base | insulin human (biosynthesis) | insulin human (genetical recombination) | insulin human isophane | insulin human [rdna origin] | insulin human, rdna origin | insulin human regular | insulin human regular (rdna) | insulin human (synthesis) | insulin injection | insulin insulatard | insulin isophane | insulin, isophane | insulin, neutral | insulin nph | insulin (ox), 8(a)-l-threonine-10(a)-l-isoleucine- | insulin recombinant human | insulin recombinant purified human | insulin regular | insulin susp isophane recombinant human | insulin susp isophane semisynthetic purified human | insulin zinc, extended | insulin zinc injection, crystalline (aqueous suspension) | insulin zinc suspension (crystalline) | insulin zinc susp recombinant human | insulin zinc susp semisynthetic purified human | insuln | ins ultrat | ins ultrat mc | insuman infusat | isophane (aqueous suspension) | isophane insulin | ly041001 | nasulin | neutral insulin | nnc 0123-0000-0338 | novolin | novolin l | novolin n | novolin r | novo mc insulin | nph | nph iletin | nph iletin ii | nph insulin | penfill | regular insulin | regular insulin, human | sar439065 | ultralente | ultralente iletin | ultralente insulin | velosulin br | velosulin br human

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