halofuginone Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Halofuginone, sold under the brand name Halocur, is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine, a natural quinazolinone alkaloid which can be found in the Chinese herb Dichroa febrifuga. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and it has received orphan drug designation from the U.S. Food and Drug Administration.   Wikipedia

Chemistry

More Chemistry

Pharmacology

Alternative names

7-bromo-6-chloro- 3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3h)- quinazolinone | 7-bromo-6-chlorofebrifugine | halofuginone | halofuginone hydrobromide | halofunginone | ht-100 | ru-19110 | stenorol | (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3h)-quinazolinone

Organizations (5)

Research & Development (5)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (3)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (3)


 

Muscular Dystrophy, Duchenne (Phase 2)

Neoplasms (Phase 1)

Sarcoma, Kaposi (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 5
  • # of Trial Organizations: 5

Trials by Phase

Trial Phase Start Date Organizations Indications

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