API | Luminespib

Luminespib Report issue

Small molecule Experimental

AACT DrugBank MeSH PubChem

Active Ingredient History

NOW

Chemistry

SMILES: CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1
InChIKey: NDAZATDQFDPQBD-UHFFFAOYSA-N
Mol. Mass: 465.55
ALogP: 4.13 Partition coefficient
ChEMBL Molecule:
luminespib

More Chemistry

Pharmacology

Mechanisms of Action:
- Heat shock protein HSP 90-alpha (Homo sapiens) ^UniProt
- Heat shock protein HSP 90-beta (Homo sapiens) ^UniProt
- Putative heat shock protein HSP 90-beta 2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide | auy922 | nvp-auy922 | ver52296 | ver 52296 | ver-52296

Organizations (21)

Research & Development (21)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (19)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (19)

Adenocarcinoma (Phase 1)

Adenocarcinoma of Lung (Phase 1/Phase 2)

Breast Neoplasms (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Colonic Neoplasms (Phase 1)

Colorectal Neoplasms (Phase 1)

Esophageal Neoplasms (Phase 2)

Gastrointestinal Stromal Tumors (Phase 2)

Hematologic Neoplasms (Phase 1/Phase 2)

Lung Neoplasms (Phase 1)

Lymphoma (Phase 2)

Lymphoma, Large-Cell, Anaplastic (Phase 1)

Multiple Myeloma (Phase 1/Phase 2)

Myeloproliferative Disorders (Phase 2)

Neoplasm Metastasis (Phase 2)

Neoplasms (Phase 1)

Pancreatic Neoplasms (Phase 2)

Small Cell Lung Carcinoma (Phase 2)

Stomach Neoplasms (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 24
# of Trial Organizations: 21

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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