homatropine Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Homatropine (used in a form of bromide or methylbromide salts) is an analogue of atropine, which acts as an antagonist of muscarinic receptors. Homatropine was approved for the treatment of cough in combination with hydrocodone bitartrate.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Combination drugs

( hydrocodone (hycodan), homatropine - other name: tussigon )

Alternative names

3-alpha-hydroxy-8-methyl-1-alpha-h,5-alpha-h-tropanium bromide mandelate | 8-methylhomatropinium bromide | ak-homatropine | americal brand of homatropine hydrobromide | dl-homatropine hydrobromide | equipin | hmbromide | homapin | homapin-10 | homapin-5 | homatropin | homatropine | (+/-)-homatropine | homatropine, (3(s)-endo)-isomer | homatropine, exo-(+-)-isomer | homatropine hydrobromide | homatropine hydrobromide, (endo-(+-)-isomer) | homatropine hydrochloride, (endo-(+-)-isomer) | homatropine merck | homatropine methylbromide | homatropine methylbromide, (3(r)-endo)-isomer | homatropine methylbromide, (3(s)-endo)-isomer | homatropine methylbromide, endo-(+-)-isomer | homatropine methylbromide iodide, (3(r)-endo)-isomer | homatropine methylbromide iodide, (3(s)-endo)-isomer | homatropine sulfate | homatropine sulfate (1:1), (3(r)-endo)-isomer | homatropine sulfate (1:1), (3(s)-endo)-isomer | homatropine sulfate (2:1), endo-isomer | homatropini methylbromidum | homatropin - pos | homoatropine | i - homatrine | isopto homatropine | mandelyltropeine | (+/-)-mandelyltropine | methatropine | methylbromure d'homatropine | methylhomatropine | methylhomatropine bromide | methylhomatropinum bromatum | methyloctatropine bromide | metilbromuro de homatropina | minims-homatropin | minims-homatropine hydrobromide | omatropina metilbromuro | tropine mandelate | tropinium methobromide mandelate

Organizations (19)

Research & Development (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (17)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (3)

Approved Indications (2)


 

Cough (approved 1983)

Pain

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Headache (Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 2
  • # of Trial Organizations: 2

Trials by Phase

Trial Phase Start Date Organizations Indications

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