Active Ingredient History
Leptin is a hormone predominantly made by adipose cells and enterocytes in the small intestine that helps to regulate energy balance by inhibiting hunger, which in turn diminishes fat storage in adipocytes. Leptin is coded for by the LEP gene. Leptin acts on cell receptors in the arcuate and ventromedial nuclei, as well as other parts of the hypothalamus and dopaminergic neurons of the ventral tegmental area, consequently mediating feeding. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Body Weight (Phase 1)
Deficiency Diseases (Phase 2)
Diabetes Mellitus, Type 1 (Phase 1)
Endothelial Cells (Phase 1)
Healthy Volunteers (Phase 4)
HIV-Associated Lipodystrophy Syndrome (Phase 2)
Insulin Resistance (Phase 2/Phase 3)
Leptin (Phase 3)
Lipodystrophy (Phase 3)
Lipodystrophy, Congenital Generalized (Phase 2/Phase 3)
Obesity (Phase 3)
Overweight (Phase 1/Phase 2)
Syndrome (Phase 2)
Vasodilation (Early Phase 1)
Venous Cutdown (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
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