API | hsp70

hsp70 Report issue

Vaccine Experimental

AACT PubChem

Active Ingredient History

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The 70 kilodalton heat shock proteins are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. Intracellularly localized Hsp70s are an important part of the cell's machinery for protein folding, performing chaperoning functions, and helping to protect cells from the adverse effects of physiological stresses. Additionally, membrane-bound Hsp70s have been identified as a potential target for cancer therapies and their extracellularly localized counterparts have been identified as having both membrane-bound and membrane-free structures. ^Wikipedia

Chemistry

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Pharmacology

Mechanism of Action:
- Heat shock 70 kDa protein 1A (Homo sapiens) ^UniProt
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hsp70

Organizations (1)

Research & Development (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)

Breast Neoplasms (Phase 1/Phase 2)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 1)

Overview

Highest Phase: Phase 2
# of Trials: 2
# of Trial Organizations: 1

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

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