Active Ingredient History
There is no information in the literature about pharmacological and biological application of definite isomer: R of valganciclovir. However, is known, that valganciclovir, existing, as a mixture of R and S diasteriomers, is the active ingredient in Valcyte, which is used as an antiviral medication given to patients who have a high chance of developing cytomegalovirus (CMV) disease after receiving a heart, kidney, or kidney-pancreas transplant. It was proposed, that stable aqueous solutions of valganciclovir can be prepared in aqueous solutions at acidic pHs but these solutions will exist as a mixture of isomers: R and S NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Cytomegalovirus Infections (approved 2001)
Cytomegalovirus Retinitis (approved 1994)
Keratitis, Herpetic (approved 1995)
Acne Vulgaris (Phase 2)
Acquired Immunodeficiency Syndrome (Phase 3)
Acute Kidney Injury (Phase 4)
Acute Lung Injury (Phase 2)
Adenovirus Infections, Human (Phase 3)
Anus Neoplasms (Phase 1)
Brain Diseases (Phase 1)
Brain Neoplasms (Phase 1)
Breast Neoplasms (Phase 1)
Burkitt Lymphoma (Phase 2)
Carcinoma, Hepatocellular (Phase 2)
Colitis (Phase 1)
Conjunctivitis (Phase 4)
Critical Illness (Phase 2)
Cytomegalovirus Infections (Phase 4)
Cytomegalovirus Retinitis (Phase 4)
Diabetes Mellitus, Type 1 (Phase 2)
DNA Virus Infections (Phase 4)
Dry Eye Syndromes (Phase 2)
Fallopian Tube Neoplasms (Phase 2)
Gastrointestinal Diseases (Phase 2)
Graft vs Host Disease (Phase 2)
Hamartoma (Phase 2)
Hematologic Diseases (Phase 4)
Hematopoietic Stem Cell Transplantation (Phase 3)
Herpesviridae Infections (Phase 4)
HIV Infections (Phase 4)
Infections (Phase 4)
Intestinal Neoplasms (Phase 1)
Keratoconjunctivitis Sicca (Phase 2)
Kidney Diseases (Phase 1/Phase 2)
Kidney Transplantation (Phase 1/Phase 2)
Leukemia (Phase 2)
Liver Neoplasms (Phase 2)
Liver Transplantation (Phase 1)
Lung Diseases (Phase 3)
Lymphoid Tissue (Phase 2)
Lymphoma (Phase 2)
Lymphoproliferative Disorders (Phase 1)
Melanoma (Phase 1)
Mesothelioma, Malignant (Phase 1)
Multiple Myeloma (Phase 2)
Multiple Organ Failure (Phase 4)
Myelodysplastic Syndromes (Phase 2)
Myeloproliferative Disorders (Phase 2)
Neoplasm Metastasis (Phase 1)
Neuroblastoma (Phase 1)
Organ Transplantation (Phase 4)
Ovarian Neoplasms (Phase 2)
Penile Neoplasms (Phase 1)
Pneumonia, Viral (Phase 4)
Precancerous Conditions (Phase 1)
Radiculopathy (Phase 1)
Respiratory Distress Syndrome (Phase 2)
Respiratory Insufficiency (Phase 2)
Sarcoma (Phase 1)
Squamous Cell Carcinoma of Head and Neck (Phase 1)
Transplantation (Phase 3)
Uterine Cervical Neoplasms (Phase 1)
Uveitis (Phase 2/Phase 3)
Varicella Zoster Virus Infection (Phase 2)
Virus Shedding (Phase 4)
Vulvar Neoplasms (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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