Active Ingredient History
Botulinum toxin, or botulinum neurotoxin, is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine release inhibitor and a neuromuscular blocking agent. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Arteries (Phase 2)
Beckwith-Wiedemann Syndrome (Phase 3)
Blepharitis (Phase 3)
Blepharospasm (Phase 4)
Botulinum Toxins (Phase 2)
Botulinum Toxins, Type A (Phase 4)
Brain Injuries, Traumatic (Phase 2)
Bruxism (Phase 3)
Cerebral Palsy (Phase 3)
Chronic Exertional Compartment Syndrome (Phase 2)
Complex Regional Pain Syndromes (Early Phase 1)
Cystitis, Interstitial (Early Phase 1)
Dermatology (Phase 2/Phase 3)
Dyspareunia (Phase 4)
Electromyography (Phase 3)
Epidermolysis Bullosa Simplex (Phase 2/Phase 3)
Erectile Dysfunction (Phase 2)
Facial Pain (Phase 2)
Fasciitis, Plantar (Phase 2)
Fecal Incontinence (Phase 3)
Hemifacial Spasm (Phase 4)
Hernia, Abdominal (Phase 2)
Hernia, Ventral (Phase 2)
Hyperhidrosis (Phase 3)
Jaw (Phase 2)
Leg Injuries (Phase 4)
Muscle Spasticity (Phase 4)
Musculoskeletal Diseases (Phase 3)
Neoplasms (Phase 3)
Pain (Phase 3)
Pelvic Floor Disorders (Phase 3)
Pelvic Pain (Phase 4)
Pelvis (Phase 4)
Popliteal Artery Entrapment Syndrome (Phase 2)
Post-Traumatic Headache (Phase 4)
Prostatic Hyperplasia (Phase 4)
Raynaud Disease (Phase 4)
Rhytidoplasty (Phase 4)
Sclerosis (Phase 3)
Scoliosis (Phase 4)
Shoulder Pain (Phase 4)
Spastic Paraplegia, Hereditary (Phase 2/Phase 3)
Strabismus (Phase 3)
Stroke (Phase 4)
Talipes (Phase 4)
Urinary Bladder, Overactive (Phase 4)
Urinary Incontinence (Phase 1/Phase 2)
Urinary Incontinence, Stress (Phase 3)
Urinary Incontinence, Urge (Phase 3)
Urination Disorders (Early Phase 1)
Trial | Phase | Start Date | Organizations | Indications |
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