Active Ingredient History
Travoprost, an isopropyl ester prodrug, is a synthetic prostaglandin F2 alpha analogue that is rapidly hydrolyzed by esterases in the cornea to its biologically active free acid. The travoporst free acid is potent and highly selective for the FP prostanoid receptor. Travoprost free acid is a selective FP prostanoid receptor agonist and is believed to reduce intraocular pressure by increasing the drainage of aqueous humor, which is done primarily through increased uveoscleral outflow and to a lesser extent, trabecular outflow facility. Travoprost ophthalmic solution is used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication. Travoprost is known by the brand names of Travatan and Travatan Z, manufactured by Alcon. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
---|
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
---|
Blood Pressure (Phase 4)
Corneal Diseases (Phase 2)
Dry Eye Syndromes (Phase 4)
Exfoliation Syndrome (Phase 3)
Glaucoma ()
Glaucoma, Angle-Closure (Phase 4)
Graves Ophthalmopathy (Phase 4)
Hyperemia (Phase 4)
Intraocular Pressure (Phase 4)
Lasers (Phase 4)
Lasers, Excimer (Phase 4)
Low Tension Glaucoma (Phase 4)
Macular Edema (Phase 4)
Pediatrics (Phase 3)
Pigmentation (Phase 4)
Uveitis, Anterior (Phase 4)
Vitiligo (Phase 4)
Trial | Phase | Start Date | Organizations | Indications |
---|
Feedback
Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).
Report issue