fospropofol (lusedra) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Fospropofol (INN), often used as the disodium salt is an intravenous sedative-hypnotic agent. It is currently approved for use in sedation of adult patients undergoing diagnostic or therapeutic procedures such as endoscopy.   Wikipedia

Chemistry

  • SMILES: CC(C)c1cccc(C(C)C)c1OCOP(=O)(O)O
  • InChIKey: QVNNONOFASOXQV-UHFFFAOYSA-N
  • Mol. Mass: 288.28
  • ALogP: 3.38
  • ChEMBL Molecules:
    fospropofol  
    fospropofol disodium  
More Chemistry

Pharmacology

Alternative names

aquavan | fospropofol | fospropofol disodium | fospropofol sodium | gpi15715 | gpi 15715 | lusedra | methanol, (2,6-bis(1-methylethyl)phenoxy)-, dihydrogen phosphate, disodium salt

Organizations (14)

Research & Development (14)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (19)

Approved Indications (1)


 

Conscious Sedation (approved 2008)

Experimental Indications - Clinical Trial Phases 1-4 (19)


 

Anesthesia (Phase 4)

Angioplasty (Phase 3)

Arthroscopy (Phase 3)

Bronchoscopy (Phase 3)

Bunion (Phase 3)

Carpal Tunnel Syndrome (Phase 3)

Catheters (Phase 3)

Colonic Polyps (Phase 3)

Colonoscopy (Phase 3)

Conscious Sedation (Phase 4)

Coronary Artery Bypass (Phase 2)

Coronary Artery Disease (Phase 2)

Intubation (Phase 2)

Lactation Disorders (Phase 1)

Orthopedic Procedures (Phase 4)

Osteotomy (Phase 3)

Pain (Phase 4)

Pharmacological and Toxicological Phenomena (Phase 1)

Respiration, Artificial (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 21
  • # of Trial Organizations: 14

Trials by Phase

Trial Phase Start Date Organizations Indications

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