7-hydroxystaurosporine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Chemistry

  • SMILES: CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)N[C@H]4O
  • InChIKey: PBCZSGKMGDDXIJ-KRUBCLEUSA-N
  • Mol. Mass: 482.54
  • ALogP: 3.84
  • ChEMBL Molecule:
    ucn-01  
More Chemistry

Pharmacology

Alternative names

7-hydroxystaurosporine | 7-hydroxy-staurosporine | (7s)-hydroxyl-staurosporine | 8,12-epoxy-1h,8h-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)triinden-1-one, 2,3,9,10,11,12-hexahydro-3-hydroxy-9-methoxy-8-methyl-10-(methylamino)- | krx-0601 | kw-2401 | ucn 01 | ucn-01 | ucn 02 | ucn-02

Organizations (14)

Research & Development (14)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (52)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (52)


 

Appendix (Phase 1)

Bile Duct Neoplasms (Phase 1)

Breast Neoplasms (Phase 1)

Carcinoma, Adenoid Cystic (Phase 1)

Carcinoma, Basal Cell (Phase 1)

Carcinoma, Mucoepidermoid (Phase 1)

Carcinoma, Non-Small-Cell Lung (Phase 1)

Carcinoma, Squamous Cell (Phase 1)

Carcinoma, Verrucous (Phase 1)

Colonic Neoplasms (Phase 1)

Colorectal Neoplasms (Phase 1)

Endometrial Neoplasms (Phase 1)

Esophageal Neoplasms (Phase 1)

Fallopian Tube Neoplasms (Phase 2)

Gallbladder Neoplasms (Phase 1)

Gastrointestinal Stromal Tumors (Phase 1)

Graft vs Host Disease (Phase 1)

Granuloma (Phase 1)

Hamartoma (Phase 2)

Intestinal Neoplasms (Phase 1)

Kidney Neoplasms (Phase 2)

Leukemia (Phase 1/Phase 2)

Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1)

Leukemia-Lymphoma, Adult T-Cell (Phase 1)

Leukemia, Monocytic, Acute (Phase 1)

Leukemia, Myeloid, Acute (Phase 1)

Leukemia, Myeloid, Chronic-Phase (Phase 1)

Leukemia, Myelomonocytic, Acute (Phase 1)

Liver Neoplasms (Phase 1)

Lymphoma (Phase 1/Phase 2)

Lymphoma, Large-Cell, Anaplastic (Phase 2)

Lymphoma, T-Cell (Phase 2)

Melanoma (Phase 2)

Myelodysplastic Syndromes (Phase 1)

Myeloproliferative Disorders (Phase 1)

Nasopharyngeal Neoplasms (Phase 1)

Neoplasm Metastasis (Phase 1)

Neoplasms (Phase 1)

Neuroblastoma (Phase 1)

Oropharyngeal Neoplasms (Phase 1)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 2)

Papilloma, Inverted (Phase 1)

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Phase 1)

Prostatic Neoplasms (Phase 1)

Rectal Neoplasms (Phase 1)

Salivary Gland Neoplasms (Phase 1)

Small Cell Lung Carcinoma (Phase 2)

Squamous Cell Carcinoma of Head and Neck (Phase 1)

Stomach Neoplasms (Phase 1)

Triple Negative Breast Neoplasms (Phase 1)

Uterine Cervical Neoplasms (Phase 1)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 22
  • # of Trial Organizations: 14

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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