API | flumatinib

flumatinib Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW

Chemistry

SMILES: CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc3cnc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1
InChIKey: BJCJYEYYYGBROF-UHFFFAOYSA-N
Mol. Mass: 562.6
ALogP: 5.0 Partition coefficient
ChEMBL Molecule:
flumatinib

More Chemistry

Pharmacology

Mechanism of Action:
- Tyrosine-protein kinase ABL1 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

Organizations (12)

Research & Development (12)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (12)

Approved Indications (1)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Experimental Indications - Clinical Trial Phases 1-4 (12)

Drugs, Investigational (Phase 4)

Fusion Proteins, bcr-abl (Phase 4)

Imatinib Mesylate (Phase 4)

Leukemia (Phase 2)

Leukemia, Lymphocytic, Chronic, B-Cell ()

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 4)

Leukemia, Myeloid, Acute (Phase 4)

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (Phase 4)

Leukemia, Myeloid, Chronic-Phase (Phase 4)

Philadelphia Chromosome (Phase 2)

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Phase 4)

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Phase 2)

Overview

Highest Phase: Phase 4
# of Trials: 10
# of Trial Organizations: 12

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue