carbetocin (Pabal) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Carbetocin, sold under the brand names Pabal among others, is a medication used to prevent excessive bleeding after childbirth, particularly following Cesarean section. It appears to work as well as oxytocin. Due to it being less economical than other options, use is not recommended by NHS Scotland. It is given by injection into a vein or muscle.   Wikipedia

Chemistry

  • SMILES: CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)CCCSC[C@H](NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCC(=O)N)NC1=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N
  • InChIKey: NSTRIRCPWQHTIA-DTRKZRJBSA-N
  • Mol. Mass: 988.18
  • ALogP: -2.5
  • ChEMBL Molecule:
    carbetocin  
More Chemistry

Pharmacology

Alternative names

1-butanoic acid-2-(o-methyl-l-tyrosine)-1-carbaoxytocin | 1-butyric acid-2-(3-(p-methoxyphenyl)-l-alanine)oxytocin | 1-carbaoxytocin, 1-butanoic acid-2-(o-methyl-l-tyrosine)- | 1-deamino-1-monocarba-2-(tyr(ome))-oxytocin | carbetocin | carbetocino | carbetocinum | dcomot | deamino-2-o-methyltyrosine-1-carbaoxytocin | depotocin | duratocin | fe 992097 | oxytocin, 1-desamino-1-monocarba-(tyr(ome))(2)- | oxytocin, 1-desamino-1-monocarba-(tyrosine(o-methyl))(2)- | pabal

Organizations (59)

Research & Development (59)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (23)

Approved Indications (1)


 

Postpartum Hemorrhage

Experimental Indications - Clinical Trial Phases 1-4 (23)


 

Anemia (Phase 4)

Anesthesia (Phase 4)

Arrhythmias, Cardiac (Phase 4)

Blood Loss, Surgical (Phase 4)

Bronchiectasis (Phase 4)

Cardiovascular Diseases (Phase 4)

Cesarean Section (Phase 4)

Delivery, Obstetric (Phase 3)

Hemodynamics (Phase 4)

Hemorrhage (Phase 4)

Leiomyoma (Phase 1)

Myoma (Phase 4)

Obstetrics (Phase 3)

Pharmacokinetics (Phase 4)

Postpartum Hemorrhage (Phase 4)

Prader-Willi Syndrome (Phase 3)

Pre-Eclampsia (Phase 3)

Pregnancy (Phase 4)

Pregnancy Complications (Phase 4)

Pregnancy, High-Risk (Early Phase 1)

Primary Prevention (Phase 4)

Uterine Inertia (Phase 4)

Uterine Myomectomy (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 72
  • # of Trial Organizations: 59

Trials by Phase

Trial Phase Start Date Organizations Indications

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