Active Ingredient History
Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic pathogens. It was first approved by the FDA on August 27, 2018. Eravacycline disrupts bacterial protein synthesis by binding to the 30S ribosomal subunit thus preventing the incorporation of amino acid residues into elongating peptide chains. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Intraabdominal Infections (approved 2018)
Appendicitis (Phase 3)
Bacterial Infections (Phase 3)
Healthy Volunteers (Phase 1)
Hematologic Neoplasms (Phase 2)
Kidney Failure, Chronic (Phase 1)
Liver Diseases (Phase 1)
Neutropenia (Phase 2)
Pharmacology (Phase 1)
Urinary Tract Infections (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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