Active Ingredient History
Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer. Epinastine is a topically active, direct H1-receptor antagonist and an inhibitor of the release of histamine from the mast cell. Epinastine is selective for the histamine H1-receptor and has affinity for the histamine H2 receptor. Epinastine also possesses affinity for the α1-, α2-, and 5-HT2 –receptors. Epinastine does not penetrate the blood/brain barrier and, therefore, is not expected to induce side effects of the central nervous system. Elestat ophthalmic solution is indicated for the prevention of itching associated with allergic conjunctivitis. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Conjunctivitis, Allergic (Phase 4)
Dermatitis, Atopic (Phase 3)
Healthy Volunteers (Phase 1)
Hypersensitivity (Phase 4)
Rhinitis, Allergic (Phase 2)
Rhinitis, Allergic, Perennial (Phase 3)
Rhinitis, Allergic, Seasonal (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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