Active Ingredient History
Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane. They are also a member of the lecithin group of yellow-brownish fatty substances occurring in animal and plant tissues. Dipalmitoylphosphatidylcholine (lecithin) is a major component of the pulmonary surfactant, and is often used in the lecithin–sphingomyelin ratio to calculate fetal lung maturity. While phosphatidylcholines are found in all plant and animal cells, they are absent in the membranes of most bacteria, including Escherichia coli. Purified phosphatidylcholine is produced commercially. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Abdominal Pain (Phase 2)
Attention Deficit and Disruptive Behavior Disorders (Phase 1/Phase 2)
Chemical and Drug Induced Liver Injury (Phase 3)
Colitis, Ulcerative (Phase 3)
Colorectal Neoplasms (Phase 2)
Diarrhea (Phase 2)
Endometrial Neoplasms (Phase 2)
Head and Neck Neoplasms (Phase 2)
Healthy Volunteers (Phase 1)
Hepatitis, Autoimmune (Phase 3)
HIV Infections (Phase 1)
Hyperlipidemias (Phase 2/Phase 3)
Intestine, Large (Phase 2)
Liver Diseases (Phase 3)
Liver Neoplasms (Phase 2)
Lung Neoplasms (Phase 2)
Melanoma (Phase 2)
Mesothelioma, Malignant (Phase 1)
Neoplasms (Phase 2)
Nerve Sheath Neoplasms (Phase 4)
Non-alcoholic Fatty Liver Disease (Phase 3)
Osteoarthritis, Knee (Phase 4)
Pancreatic Neoplasms (Phase 2)
Phosphatidylcholines (Phase 2)
Schizophrenia (Phase 1/Phase 2)
Testicular Neoplasms (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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