Active Ingredient History
Silver diammine fluoride (SDF), also known as silver diamine fluoride in most of the dental literature, is a topical medication used to treat and prevent dental caries and relieve dentinal hypersensitivity. It is a colorless or blue-tinted, odourless liquid composed of silver, ammonium and fluoride ions at a pH of 10.4 or 13. Ammonia compounds reduce the oxidative potential of SDF, increase its stability and helps to maintain a constant concentration over a period of time, rendering it safe for use in the mouth. Silver and fluoride ions possess antimicrobial properties and are used in the remineralization of enamel and dentin on teeth for preventing and arresting dental caries. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Child Behavior (Phase 4)
Dental Caries (Phase 4)
Dental Pulp (Phase 2/Phase 3)
Dentin (Phase 2/Phase 3)
Dentist's Role (Phase 2)
Fluorides (Early Phase 1)
Gastrointestinal Microbiome (Phase 3)
Pediatrics (Phase 2/Phase 3)
Quality of Life (Phase 4)
Tooth (Phase 3)
Tooth, Deciduous (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
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