defibrotide (defitelio) Report issue

Animal product Orphan Drug FDA Approved FDA Fast Track FDA Priority Review FDA

Active Ingredient History

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Defibrotide, sold under the brandname Defitelio, is a mixture of single-stranded oligonucleotides that is purified from the intestinal mucosa of pigs. It is used to treat veno-occlusive disease of the liver of people having had a bone marrow transplant, with different limitations in the US and the European Union. It works by protecting the cells lining blood vessels in the liver and preventing blood clotting; the way it does this is not well understood.   Wikipedia

More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Missing data
  • Pro Drug: No

Drug Pricing (per unit)

More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

defibrinotide | defibrotide | defibrotide (bovine) | defibrotide sodium | defitelio | jzp381 | jzp-381

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