Active Ingredient History
Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide that are bacterial toxins. They are composed of an O-antigen, an outer core, and an inner core all joined by covalent bonds, and are found in the bacterial capsule, the outermost membrane of cell envelope of Gram-negative bacteria, such as E. coli and Salmonella. Today, the term endotoxin is often used synonymously with LPS, although there are a few endotoxins that are not related to LPS, such as the so-called delta endotoxin proteins produced by Bacillus thuringiensis. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Abdominal Neoplasms (Phase 1)
Alzheimer Disease (Early Phase 1)
Arthritis, Rheumatoid (Phase 1)
Asthma (Phase 1)
Autoimmune Diseases (Early Phase 1)
Cannabidiol (Early Phase 1)
Cardiovascular Diseases (Phase 1)
Depression (Early Phase 1)
Depressive Disorder, Major (Phase 1/Phase 2)
Endotoxemia (Phase 4)
Escherichia coli Infections (Phase 4)
Fibromyalgia (Phase 2/Phase 3)
Healthy Volunteers (Phase 4)
Hyperoxia (Phase 1/Phase 2)
Hypoxia (Phase 1/Phase 2)
Immunity, Innate (Phase 1)
Infections (Early Phase 1)
Inflammation (Phase 1)
Lung Diseases (Phase 1)
Melanoma (Phase 1)
Neoplasms (Phase 1)
Oxygen Saturation (Phase 1/Phase 2)
Regional Blood Flow (Phase 4)
Retina (Phase 4)
Schizophrenia (Phase 1)
Sepsis (Phase 2/Phase 3)
Stress Disorders, Post-Traumatic (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
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