desogestrel (Mercilon) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Ethinylestradiol/etonogestrel, sold under the brand names NuvaRing among others, is a hormonal vaginal ring used for birth control and to improve menstrual symptoms. It contains ethinylestradiol, an estrogen, and etonogestrel, a progestin. It is used by insertion into the vagina. Pregnancy occurs in about 0.3% of women with perfect use and 9% of women with typical use.   Wikipedia

Chemistry

  • SMILES: CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
  • InChIKey: GCKFUYQCUCGESZ-BPIQYHPVSA-N
  • Mol. Mass: 324.46
  • ALogP: 4.05
  • ChEMBL Molecules:
    etonogestrel  
    desogestrel  
    implanon  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Parenteral, Topical
  • Pro Drug: No

Combination drugs

( ethinyl estradiol (Estinyl), desogestrel (Mercilon) - other names: bekyree, cyclessa, desogestrel; ethinyl, emoquette, enskyce, isibloom, kalliga, kariva, kimidess, mircette, nuvaring, ortho-cept, pimtrea, velivet, viorele, volnea )

Alternative names

13-ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-ketodesogestrel | 3-keto-desogestrel | 3-oxodesogestrel | 3-oxo desogestrel | aizea | cerazette | cerelle | combeq | combiphasic ee-dsg contraceptive | desogestrel | desogestrelum | desomono | ethinyl estradiol-desogestrel combination | ethonogestrel | etonogestrel | étonogestrel | etonogestrelum | etonorgestrel | feanolla | implanon | mercilon | nacrez | nexplanon | nourypharma brand of 3-keto-desogestrel | nuvaring | org 2969 | org-2969 | org-3236 | organon brand of 3-keto-desogestrel | zelleta

Organizations (96)

Research & Development (80)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (20)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (48)

Approved Indications (1)


 

Pregnancy (approved 1992)

Experimental Indications - Clinical Trial Phases 1-4 (48)


 

Abortion, Induced (Phase 4)

Acne Vulgaris (Phase 4)

Adolescent (Phase 4)

Anemia, Sickle Cell (Phase 4)

Biological Availability (Phase 1)

Chlamydia Infections (Phase 4)

Contraception (Phase 4)

Contraception, Postcoital (Phase 4)

Contraceptive Agents (Phase 4)

Contraceptives, Oral (Phase 3)

Drug-Related Side Effects and Adverse Reactions (Phase 4)

Dysmenorrhea (Phase 4)

Endometriosis (Phase 4)

Exercise (Phase 3)

Family Planning Services (Phase 3)

Fertilization in Vitro (Phase 4)

Growth and Development (Phase 4)

Healthy Volunteers (Phase 4)

Hemorrhage (Phase 4)

Hemostasis (Phase 2)

HIV (Phase 4)

HIV Infections (Phase 4)

Infertility (Phase 4)

Infertility, Female (Phase 3)

Lactation Disorders (Phase 4)

Leiomyoma (Phase 4)

Light (Phase 4)

Live Birth (Phase 4)

Medicine, Chinese Traditional (Phase 4)

Menstruation Disturbances (Phase 4)

Metrorrhagia (Phase 3)

Neisseriaceae Infections (Phase 4)

Opioid-Related Disorders (Phase 4)

Ovarian Diseases (Phase 2)

Ovarian Follicle (Phase 1)

Ovulation Induction (Phase 1/Phase 2)

Polycystic Ovary Syndrome (Phase 4)

Postpartum Period (Phase 4)

Pregnancy (Phase 4)

Pregnancy Complications (Phase 4)

Premenstrual Syndrome (Phase 4)

Primary Ovarian Insufficiency (Phase 3)

Prostatic Neoplasms (Phase 2)

Sexual Behavior (Phase 4)

Sleep Apnea, Central (Phase 2/Phase 3)

Therapeutic Equivalency (Phase 1)

Thinness (Phase 4)

Vaginosis, Bacterial (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 97
  • # of Trial Organizations: 80

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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