Active Ingredient History
Clodronic acid (INN) or clodronate disodium (Na2CH2Cl2O6P2) (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its anti-inflammatory effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-α. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Breast Neoplasms (Phase 3)
Hip Injuries (Early Phase 1)
Osteoporosis, Postmenopausal (Phase 3)
Osteoradionecrosis (Phase 3)
Pain (Phase 3)
Prostatic Neoplasms (Phase 3)
Prostheses and Implants (Phase 2)
Quality of Life (Phase 3)
Radiation Oncology (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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