chenodeoxycholic acid (Chenix) Report issue

Small molecule Approved FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Chenodeoxycholic acid is a bile acid. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids. It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name.   Wikipedia

Chemistry

  • SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
  • InChIKey: RUDATBOHQWOJDD-BSWAIDMHSA-N
  • Mol. Mass: 392.58
  • ALogP: 4.48
  • ChEMBL Molecule:
    chenodiol  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Alternative names

3alpha,7alpha-dihydroxy-5beta-cholanic acid | 7alpha-hydroxylithocholic acid | anthropodeoxycholic acid | anthropodesoxycholic acid | anthropododesoxycholic acid | cdca | chendol 125 | chendol 250 | chenic acid | chenix | chenocedon | chenocholic acid | chenodeoxycholate | chenodeoxycholic acid | chenodesoxycholic acid | chenodiol | chenofalk | combidol | gallodesoxycholic acid | lithofalk | sodium chenodeoxycholate | xenbilox

Organizations (17)

Research & Development (13)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (4)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (11)

Approved Indications (1)


 

Gallstones (approved 1983)

Experimental Indications - Clinical Trial Phases 1-4 (10)


 

Bile Acids and Salts (Phase 4)

Cholelithiasis (Phase 4)

Constipation (Phase 2)

Echolocation (Phase 1)

Hyperlipidemia, Familial Combined (Early Phase 1)

Hyperlipoproteinemia Type IV (Early Phase 1)

Metabolic Syndrome (Early Phase 1)

Obesity, Morbid (Phase 4)

Spastic Paraplegia, Hereditary (Phase 2)

Xanthomatosis, Cerebrotendinous (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 14
  • # of Trial Organizations: 13

Trials by Phase

Trial Phase Start Date Organizations Indications

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