Active Ingredient History
Cetylpyridinium chloride (CPC) is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis. It has also been used as an ingredient in certain pesticides. Though one study seems to indicate cetylpyridinium chloride does not cause brown tooth stains, at least one mouthwash containing CPC as an active ingredient bears the warning label "In some cases, antimicrobial rinses may cause surface staining to teeth," following a failed class-action lawsuit brought by customers whose teeth were stained. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Antisepsis ()
Common Cold (Phase 3)
Coronavirus (Phase 4)
Coronavirus Infections (Phase 2)
COVID-19 (Phase 4)
Dental Caries (Phase 4)
Dental Plaque (Phase 4)
Gingivitis (Phase 4)
Healthy Volunteers (Phase 3)
Hygiene (Phase 3)
Infant, Premature (Phase 2)
Mouthwashes (Phase 4)
Mucositis (Phase 2)
Pain (Phase 3)
Periodontal Diseases (Phase 4)
Periodontitis (Phase 2)
Pharyngeal Diseases (Phase 2)
Polymerase Chain Reaction (Phase 4)
Quadriceps Muscle (Early Phase 1)
Respiratory Tract Infections (Phase 2)
Saliva (Phase 4)
Sarcopenia (Early Phase 1)
SARS-CoV-2 (Phase 4)
Viral Load (Phase 4)
Virus Diseases (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
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