API | cc-115

cc-115 Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Chemistry

SMILES: CCN1C(=O)CNc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21
InChIKey: GMYLVKUGJMYTFB-UHFFFAOYSA-N
Mol. Mass: 336.36
ALogP: 1.41 Partition coefficient
ChEMBL Molecules:

cc-115

cc-115

More Chemistry

Pharmacology

Mechanisms of Action:
- DNA-dependent protein kinase catalytic subunit (Homo sapiens) ^UniProt
- Serine/threonine-protein kinase mTOR (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1h)-one | cc-115

Organizations (6)

Research & Development (6)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Glioblastoma (Phase 2)

Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1)

Neoplasm Metastasis (Phase 1)

Osteosarcoma (Phase 1)

Prostatic Neoplasms (Phase 1)

Prostatic Neoplasms, Castration-Resistant (Phase 1)

Squamous Cell Carcinoma of Head and Neck (Phase 1)

Overview

Highest Phase: Phase 2
# of Trials: 3
# of Trial Organizations: 6

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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