Active Ingredient History
Oxygen is a chemical element; it has symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as well as with other compounds. Oxygen is the most abundant element in Earth's crust, and after hydrogen and helium, it is the third-most abundant element in the universe. At standard temperature and pressure, two atoms of the element bind to form dioxygen, a colorless and odorless diatomic gas with the formula O2. Diatomic oxygen gas currently constitutes 20.95% of the Earth's atmosphere, though this has changed considerably over long periods of time. Oxygen makes up almost half of the Earth's crust in the form of oxides. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Abdominoplasty (Phase 4)
Abortion, Induced (Phase 3)
Abscess (Phase 4)
Acidosis, Respiratory (Phase 1/Phase 2)
Acne Vulgaris (Phase 2)
Acute Coronary Syndrome (Phase 3)
Acute Kidney Injury (Phase 3)
Acute Lung Injury (Phase 4)
Acute Pain (Phase 4)
Adolescent Health (Phase 2/Phase 3)
Airway Management (Phase 2)
Airway Obstruction (Phase 1/Phase 2)
Allergy and Immunology (Phase 1)
Amputation, Surgical (Phase 4)
Amyotrophic Lateral Sclerosis (Phase 1/Phase 2)
Analgesia (Phase 2/Phase 3)
Analgesics, Opioid (Phase 1/Phase 2)
Anemia (Phase 2)
Anemia, Sickle Cell (Phase 2)
Anesthesia (Phase 4)
Angina Pectoris (Phase 2)
Angina, Unstable (Phase 3)
Ankle Fractures (Phase 3)
Anxiety (Phase 4)
Anxiety Disorders (Phase 4)
Arterial Occlusive Diseases (Phase 2)
Asthma (Phase 2)
Autistic Disorder (Phase 3)
Autonomic Nervous System Diseases (Phase 1)
Bariatric Surgery (Phase 4)
Bone Marrow Transplantation (Phase 2)
Brachytherapy (Phase 2)
Brain Injuries, Traumatic (Phase 3)
Brain Injury, Chronic (Phase 2)
Brain Ischemia (Phase 2)
Brain Neoplasms (Phase 1/Phase 2)
Breast Neoplasms (Phase 3)
Bronchiolitis (Phase 4)
Bronchitis, Chronic (Phase 2/Phase 3)
Bronchopulmonary Dysplasia (Phase 3)
Bronchoscopy (Phase 3)
Burns (Phase 3)
Bursitis (Phase 4)
Carbon Monoxide Poisoning (Phase 4)
Carcinoma, Hepatocellular (Phase 1)
Carcinoma, Non-Small-Cell Lung (Phase 1)
Carcinoma, Squamous Cell (Phase 1)
Cardiomyopathies (Phase 3)
Cardiopulmonary Bypass (Phase 4)
Cardiovascular Diseases (Phase 4)
Central Nervous System Diseases (Phase 2/Phase 3)
Cerebral Arteries (Phase 2)
Cerebral Infarction (Phase 2)
Cerebral Intraventricular Hemorrhage (Phase 2/Phase 3)
Child Behavior (Phase 3)
Chlorhexidine (Phase 3)
Cluster Headache (Phase 1)
Cognition Disorders (Phase 1)
Colitis, Ulcerative (Phase 2)
Colonic Pseudo-Obstruction (Phase 1)
Communicable Diseases (Phase 3)
Contraceptive Devices (Phase 2/Phase 3)
Coronary Artery Disease (Phase 3)
Coronavirus Infections (Phase 2)
COVID-19 (Phase 4)
Critical Care (Phase 3)
Critical Illness (Phase 4)
Cystic Fibrosis (Phase 1)
Cystitis (Phase 2/Phase 3)
Cystitis, Interstitial (Early Phase 1)
Cytokine Release Syndrome (Phase 2/Phase 3)
Cytoprotection (Phase 1/Phase 2)
Decompression (Phase 1)
Decompression Sickness (Phase 2/Phase 3)
Delayed Graft Function (Phase 3)
Dental Caries (Phase 3)
Depressive Disorder, Major (Phase 4)
Depressive Disorder, Treatment-Resistant (Phase 4)
Dermatitis, Atopic (Phase 2)
Dermatitis, Seborrheic (Phase 2)
Diabetes Mellitus (Phase 3)
Diabetes Mellitus, Type 2 (Phase 1/Phase 2)
Diabetic Foot (Phase 4)
Dilatation (Early Phase 1)
Diving (Phase 2/Phase 3)
Down Syndrome (Phase 2)
Dyspnea (Phase 1/Phase 2)
Ehlers-Danlos Syndrome (Phase 4)
Emphysema (Phase 1)
Endothelial Cells (Phase 2/Phase 3)
Erectile Dysfunction (Phase 4)
Escherichia coli Infections (Phase 4)
Exercise (Phase 2)
Extracorporeal Membrane Oxygenation (Phase 4)
Familial Primary Pulmonary Hypertension (Phase 3)
Fetal Distress (Phase 3)
Fibrosis (Phase 2)
General Surgery (Phase 4)
Geriatrics (Phase 4)
Gingival Diseases (Phase 4)
Glaucoma (Phase 4)
Glioblastoma (Phase 2)
Glioma (Phase 1)
Gliosarcoma (Phase 2)
Graft vs Host Disease (Phase 3)
Gynecology (Phase 2/Phase 3)
Headache (Phase 1)
Head and Neck Neoplasms (Phase 1)
Healthy Volunteers (Phase 4)
Heart Arrest (Phase 2)
Heart Diseases (Phase 4)
Heart Failure (Phase 4)
Hematologic Neoplasms (Phase 2/Phase 3)
Hematopoietic Stem Cells (Phase 2)
Hemoglobins (Phase 2)
Hodgkin Disease (Phase 2)
Hyperalgesia (Phase 2)
Hyperbaric Oxygenation (Phase 4)
Hypercapnia (Phase 1)
Hyperoxia (Phase 4)
Hypertension, Pulmonary (Phase 4)
Hypoplastic Left Heart Syndrome (Phase 1/Phase 2)
Hypovolemia (Phase 1)
Hypoxia (Phase 2/Phase 3)
Hypoxia, Brain (Phase 4)
Idiopathic Pulmonary Fibrosis (Phase 2)
Ileus (Phase 1)
Immune System Diseases (Phase 4)
Immunocompromised Host (Phase 3)
Infant (Phase 4)
Infant, Newborn, Diseases (Phase 3)
Infant, Premature (Phase 3)
Infant, Premature, Diseases (Phase 2/Phase 3)
Infant, Small for Gestational Age (Phase 3)
Infections (Phase 3)
Inflammation (Phase 2/Phase 3)
Inflammatory Bowel Diseases (Phase 1/Phase 2)
Injection Site Reaction (Phase 3)
Intestinal Diseases (Phase 1)
Ischemic Stroke (Phase 3)
Kidney Failure, Chronic (Phase 2)
Kidney Transplantation (Phase 3)
Lacerations (Phase 4)
Laminaria (Early Phase 1)
Laparotomy (Phase 4)
Leukemia, Lymphoid (Phase 2)
Leukemia, Myeloid (Early Phase 1)
Leukemia, Myeloid, Acute (Phase 2)
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (Early Phase 1)
Leukemia, Myelomonocytic, Chronic (Early Phase 1)
Leukomalacia, Periventricular (Phase 2/Phase 3)
Live Birth (Phase 3)
Liver Diseases (Phase 4)
Long-Acting Reversible Contraception (Phase 2/Phase 3)
Lower Urinary Tract Symptoms (Phase 4)
Lumbar Vertebrae (Phase 2)
Lung Diseases (Phase 4)
Lung Diseases, Interstitial (Phase 4)
Lung Diseases, Obstructive (Phase 4)
Lung Neoplasms (Phase 1)
Lung Transplantation (Phase 2)
Lymphedema (Phase 2)
Lymphoma (Phase 2)
Lymphoma, Non-Hodgkin (Phase 2)
Mastectomy, Radical (Phase 1/Phase 2)
Meningioma (Phase 1)
Mental Disorders (Phase 4)
Metabolomics (Early Phase 1)
Migraine Disorders (Phase 2)
Mitochondria (Phase 3)
Motor Activity (Early Phase 1)
Multiple Myeloma (Phase 2)
Myelodysplastic Syndromes (Phase 2)
Myeloproliferative Disorders (Early Phase 1)
Myocardial Infarction (Phase 3)
Myocardial Ischemia (Phase 2/Phase 3)
Myocardial Reperfusion Injury (Phase 1/Phase 2)
Natriuretic Peptide, Brain (Phase 4)
Neoplasm Metastasis (Phase 3)
Neoplasms (Phase 4)
Nervous System Diseases (Phase 4)
Neuralgia (Phase 2/Phase 3)
Neurobehavioral Manifestations (Phase 4)
Neurologic Manifestations (Phase 1)
Nitrous Oxide (Early Phase 1)
Obesity (Phase 2)
Obesity, Morbid (Phase 4)
Opioid-Related Disorders (Phase 2)
Optic Neuropathy, Ischemic (Phase 3)
Osteoarthritis, Knee (Phase 2)
Osteoradionecrosis (Phase 2/Phase 3)
Oxidative Stress (Phase 4)
Oxygen (Phase 4)
Oxygen Inhalation Therapy (Early Phase 1)
Oxygen Saturation (Phase 4)
Pain (Phase 4)
Paroxysmal Hemicrania (Phase 1)
Pathologic Processes (Phase 3)
Pediatrics (Phase 1)
Peer Review, Research (Phase 3)
Peripheral Vascular Diseases (Phase 4)
Persistent Fetal Circulation Syndrome (Phase 4)
Pneumonia (Phase 3)
Pneumonia, Viral (Phase 2)
Polycythemia (Phase 2)
Post-Acute COVID-19 Syndrome (Phase 2)
Post-Concussion Syndrome (Phase 3)
Postoperative Complications (Phase 4)
Postoperative Nausea and Vomiting (Phase 3)
Postpartum Hemorrhage (Phase 4)
Prader-Willi Syndrome (Phase 4)
Pregnancy Complications (Phase 3)
Premature Birth (Phase 3)
Primary Myelofibrosis (Early Phase 1)
Prostatic Hyperplasia (Phase 4)
Prostatic Neoplasms (Phase 4)
Pulmonary Arterial Hypertension (Phase 2)
Pulmonary Atelectasis (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Pulmonary Embolism (Phase 3)
Pulmonary Fibrosis (Phase 2)
Pyoderma Gangrenosum (Phase 3)
Radiation Fibrosis Syndrome (Phase 2)
Radiation Pneumonitis (Phase 2)
Rapid Sequence Induction and Intubation (Phase 4)
Regional Blood Flow (Phase 4)
Renal Colic (Phase 2)
Reperfusion Injury (Phase 3)
Respiration, Artificial (Phase 4)
Respiratory Distress Syndrome (Phase 3)
Respiratory Insufficiency (Phase 4)
Respiratory Syncytial Virus Infections (Phase 3)
Respiratory Tract Diseases (Phase 4)
Respiratory Tract Infections (Phase 1/Phase 2)
Retina (Phase 4)
Retinal Diseases (Phase 4)
Retinitis Pigmentosa (Early Phase 1)
Retinopathy of Prematurity (Phase 3)
Rosacea (Phase 2)
Sarcoma (Phase 4)
Schizophrenia (Phase 3)
Sclerosis (Phase 3)
Seizures, Febrile (Phase 2/Phase 3)
Sepsis (Phase 4)
Severe Acute Respiratory Syndrome (Phase 2/Phase 3)
Shock, Cardiogenic (Phase 3)
Sleep (Phase 2)
Sleep Apnea, Central (Phase 4)
Sleep Apnea, Obstructive (Phase 2)
Sleep Apnea Syndromes (Phase 4)
Sleep Disorders, Intrinsic (Phase 2)
Sleep Wake Disorders (Phase 2)
Soft Tissue Injuries (Phase 2/Phase 3)
Spinal Cord Injuries (Phase 4)
Spinal Puncture (Phase 4)
Squamous Cell Carcinoma of Head and Neck (Phase 2)
Status Asthmaticus (Phase 2)
ST Elevation Myocardial Infarction (Phase 4)
Stem Cell Research (Phase 2)
Stress Disorders, Post-Traumatic (Phase 2)
Stroke (Phase 4)
Subarachnoid Hemorrhage (Phase 2)
Substance-Related Disorders (Phase 2)
Surgical Wound Infection (Phase 4)
Systemic Inflammatory Response Syndrome (Phase 4)
Thoracic Surgery (Phase 4)
Tibial Fractures (Phase 2/Phase 3)
Tinea Pedis (Phase 2)
Tonsillitis (Phase 2)
Urinary Bladder Neoplasms (Phase 3)
Urinary Incontinence, Stress (Phase 4)
Urinary Tract Infections (Early Phase 1)
Vascular Diseases (Phase 3)
Venous Thromboembolism (Early Phase 1)
Wound Infection (Phase 3)
Wounds and Injuries (Phase 4)
Xerostomia (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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