ivacaftor (Kalydeco) Report issue

Small molecule Orphan Drug FDA Approved FDA First in Class Fast Track FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

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Chemistry

Mol. Mass

392.4907

ALogP

5.08

Rule of 5

No

Rule of 3

No
Details
  • SMILES: CC(C)(C)C1=CC(=C(O)C=C1NC(=O)C2=CNC3=C(C=CC=C3)C2=O)C(C)(C)C
  • InChIKey: PURKAOJPTOLRMP-UHFFFAOYSA-N
    1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)
  • Chirality: Achiral Molecule
  • Inorganic: No
  • Polymer: No

Sources

CHEMBL2010601   ChEMBL
ivacaftor

1Y740ILL1Z   NCATS
ivacaftor *

Ivacaftor   Wikipedia

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