Active Ingredient History

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Pentetrazol (pentylenetetrazole, BTD-001) is a pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive gamma-aminobutyric acid (GABA) antagonist. Pentetrazol (pentylenetetrazole) has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility. GABA is thought to play a role in promoting sleep and its function is believed to be elevated in idiopathic hypersomnia. By blocking GABA’s function, pentetrazol (pentylenetetrazole, BTD-001) is expected to reduce excessive daytime sleepiness.   NCATS

  • SMILES: C1CCN2N=NN=C2CC1
  • InChIKey: CWRVKFFCRWGWCS-UHFFFAOYSA-N
  • Mol. Mass: 138.1704
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Missing data
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Missing data
1,5-pentamethylenetetrazole | btd-001 | cardiazole | leptazol | pentamethazol | pentazol | pentetrazol | pentylenetetrazole

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