Active Ingredient History

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  • Now
The duocarmycins are members of a series of related natural products first isolated from Streptomyces bacteria in 1978. They are notable for their extreme cytotoxicity and thus represent a class of exceptionally potent antitumour antibiotics.   Wikipedia

  • SMILES: Cc1c[nH]c2c(O)cc3N(C[C@@H](CCl)c3c12)C(=O)c4cc5cc(NC(=O)Nc6ccc7[nH]c(cc7c6)C(=O)N8C[C@@H](CCl)c9c8cc(O)c%10[nH]cc(C)c9%10)ccc5[nH]4
  • InChIKey: FONKWHRXTPJODV-DNQXCXABSA-N
  • Mol. Mass: 815.72
  • ALogP: 9.25
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
benzo(1,2-b:4,3-b')dipyrrol-4-ol, 6,6'-(carbonylbis(imino-1h-indole-5,2-diylcarbonyl))bis(8-(chloromethyl)-3,6,7,8-tetrahydro-1-methyl-, (s-(r*,r*))) | bizelesin | u 77779 | u-77779 | u-77,779 | u-78779

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