API | methylchloroisothiazolinone

methylchloroisothiazolinone Report issue

Allergen Experimental

Active Ingredient History

Methylchloroisothiazolinone is an active ingredient in many preservatives marketed under various brand names. It is effective against gram-positive and gram-negative bacteria, yeast, and fungi. Pure Methylchloroisothiazolinone is not commercially available. Kathon CG contains a mixture of Methylisothiazolinone (MI) and Methylchloroisothiazolinone (MCI) in ratio 3:1. Kathon was used in various rinse-off and leave-on formulations including hair products, shampoos, skin care products, bath products, eye and facial makeup, wet wipes and suntan products. The Commission envisages amending Annex V of the Cosmetics Regulation (EC) No. 1223/2009 to restrict the use of methylchloroisothiazolinone to rinse-off products, as suggested by the SCCS. ^NCATS

Chemistry

SMILES: CN1SC(Cl)=CC1=O
InChIKey: DHNRXBZYEKSXIM-UHFFFAOYSA-N
Mol. Mass: 149.599
ALogP: Missing data
ChEMBL Molecules: Missing data

More Chemistry

Pharmacology

Mechanisms of Action: Missing data
Multi-specific: Missing data
Black Box: Missing data
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: Missing data

Indications (1)

Approved Indications (1)

Dermatitis, Allergic Contact

Experimental Indications - Clinical Trial Phases 1-4 (0)

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