Active Ingredient History
Botulinum toxin, or botulinum neurotoxin, is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine release inhibitor and a neuromuscular blocking agent. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Blepharospasm (approved 1989)
Strabismus (approved 1989)
Acne Vulgaris (Phase 2)
Affect (Phase 1)
Aging (Phase 4)
Amputation Stumps (Phase 3)
Attention Deficit Disorder with Hyperactivity (Phase 2/Phase 3)
Bariatric Surgery (Phase 4)
Blepharitis (Phase 4)
Blepharospasm (Phase 2/Phase 3)
Blood Transfusion (Phase 1)
Botulinum Toxins (Phase 4)
Botulinum Toxins, Type A (Phase 4)
Bursitis (Early Phase 1)
Carotid Artery Diseases (Phase 1)
Carpal Tunnel Syndrome (Phase 2)
Catheterization (Phase 1)
Cerebral Palsy (Phase 4)
Cerebrovascular Disorders (Phase 4)
Chronic Exertional Compartment Syndrome (Phase 2/Phase 3)
Chronic Pain (Phase 4)
Cicatrix (Phase 3)
Cicatrix, Hypertrophic (Phase 4)
Cluster Headache (Phase 3)
Colostomy (Phase 2)
Contracture (Phase 3)
Cystitis, Interstitial (Phase 2)
Deglutition Disorders (Phase 2/Phase 3)
Depression (Phase 1)
Depressive Disorder, Major (Phase 1)
Depressive Disorder, Treatment-Resistant (Phase 1)
Dermatology (Phase 4)
Diabetes Mellitus (Phase 2)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Neuropathies (Phase 4)
Drug Misuse (Phase 2)
Dry Eye Syndromes (Phase 2/Phase 3)
Dysphonia (Phase 1/Phase 2)
Dystonia (Phase 3)
Dystonic Disorders (Phase 3)
Ectodermal Dysplasia 1, Anhidrotic (Phase 1)
Elbow (Phase 3)
Erectile Dysfunction (Phase 2/Phase 3)
Esophageal Achalasia (Phase 4)
Eye Diseases, Hereditary (Phase 4)
Face (Phase 4)
Fasciitis, Plantar (Phase 2/Phase 3)
General Surgery (Phase 2)
Gingival Diseases (Phase 3)
Gingival Overgrowth (Phase 1)
Groin (Phase 2)
Headache (Phase 3)
Headache Disorders, Secondary (Early Phase 1)
Healthy Volunteers (Phase 1)
Hemifacial Spasm (Phase 3)
Hemiplegia (Phase 4)
Hemorrhagic Stroke (Phase 1)
Hyperhidrosis (Phase 4)
Jaw (Phase 3)
Joint Diseases (Phase 2)
Keloid (Early Phase 1)
Knee (Phase 2)
Leg Injuries (Phase 4)
Magnetic Resonance Imaging (Phase 2)
Masseter Muscle (Phase 3)
Meige Syndrome (Phase 2/Phase 3)
Migraine Disorders (Phase 4)
Multiple Sclerosis (Phase 4)
Muscles (Phase 2/Phase 3)
Muscle Spasticity (Phase 4)
Myalgia (Phase 2)
Myofascial Pain Syndromes (Phase 3)
Neonatal Brachial Plexus Palsy (Phase 3)
Neoplasms (Phase 3)
Nerve Sheath Neoplasms (Phase 4)
Neuralgia (Phase 2)
Neurogenic Inflammation (Phase 2)
Nocturia (Phase 4)
Obesity (Phase 4)
Pain (Phase 4)
Pain, Postoperative (Phase 2)
Pancreatic Neoplasms (Phase 2)
Paralysis (Early Phase 1)
Parkinson Disease (Phase 2/Phase 3)
Pelvic Floor (Early Phase 1)
Pelvic Floor Disorders (Early Phase 1)
Pelvic Organ Prolapse (Phase 4)
Penicillins (Phase 1)
Postoperative Nausea and Vomiting (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 2)
Raynaud Disease (Phase 4)
Recurrence (Phase 3)
Rehabilitation (Phase 2)
Rejuvenation (Phase 4)
Rhytidoplasty (Phase 4)
Scleroderma, Systemic (Early Phase 1)
Scoliosis (Phase 2)
Scrotum (Phase 4)
Seizures (Phase 4)
Sinusitis (Phase 3)
Skin Abnormalities (Phase 1)
Skin Aging (Phase 4)
Sleep Bruxism (Phase 2)
Smiling (Phase 4)
Stroke (Phase 4)
Swallows (Phase 2/Phase 3)
Temporomandibular Joint Disorders (Phase 3)
Tendinopathy (Phase 2)
Tension-Type Headache (Phase 3)
Therapeutics (Phase 2)
Thoracic Surgery (Phase 3)
Thromboangiitis Obliterans (Phase 3)
Thumb (Phase 4)
Torticollis (Phase 3)
Tremor (Phase 2)
Trigeminal Nerve Injuries (Phase 3)
Urinary Bladder, Neurogenic (Phase 4)
Urinary Bladder, Overactive (Phase 4)
Urinary Incontinence (Phase 4)
Urinary Incontinence, Stress (Early Phase 1)
Urinary Incontinence, Urge (Phase 4)
Urination Disorders (Phase 4)
Urologic Diseases (Phase 2/Phase 3)
Venous Thrombosis (Phase 1)
Vertebral Artery Dissection (Phase 1)
Vulvodynia (Phase 3)
Weight Loss (Phase 2/Phase 3)
Wounds and Injuries (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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