API | opaganib

opaganib Report issue

Small molecule Experimental

AACT DrugBank MeSH PubChem

Active Ingredient History

NOW

Opaganib (ABC294640) is a drug which acts as an inhibitor of the enzyme sphingosine kinase 2. It is under development as a potential treatment agent for several different kinds of cancer. ^Wikipedia

Chemistry

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More Chemistry

Pharmacology

Mechanism of Action:
- Sphingosine kinase 2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
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3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide | 4-pyridinylmethyl-3-(4-chlorophenyl) adamantane carboxamide | abc294640 | abc 294640 | abc-294640

Organizations (8)

Research & Development (8)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (12)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (12)

Carcinoma, Hepatocellular (Phase 2)

Cholangiocarcinoma (Phase 2)

Coronavirus Infections (Phase 2)

COVID-19 (Phase 2/Phase 3)

Klatskin Tumor (Phase 2)

Lymphoma, Large B-Cell, Diffuse (Phase 1/Phase 2)

Multiple Myeloma (Phase 1/Phase 2)

Neoplasms (Phase 1)

Pancreatic Neoplasms (Phase 1)

Prostatic Neoplasms (Phase 2)

Respiratory Tract Infections (Phase 2/Phase 3)

Sarcoma, Kaposi (Phase 1/Phase 2)

Overview

Highest Phase: Phase 3
# of Trials: 10
# of Trial Organizations: 8

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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