API | beta-hydroxybutyrate

beta-hydroxybutyrate Report issue

Small molecule Experimental

AACT PubChem

Active Ingredient History

NOW

β-Hydroxybutyric acid, also known as 3-hydroxybutyric acid or BHB, is an organic compound and a beta hydroxy acid with the chemical formula CH3CH(OH)CH2CO2H; its conjugate base is β-hydroxybutyrate, also known as 3-hydroxybutyrate. β-Hydroxybutyric acid is a chiral compound with two enantiomers: D-β-hydroxybutyric acid and L-β-hydroxybutyric acid. Its oxidized and polymeric derivatives occur widely in nature. In humans, D-β-hydroxybutyric acid is one of two primary endogenous agonists of hydroxycarboxylic acid receptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor (GPCR). ^Wikipedia

Chemistry

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Pharmacology

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beta-hydroxybutyrate

Organizations (17)

Research & Development (17)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (4)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (4)

Amyotrophic Lateral Sclerosis (Phase 2)

Brain Injuries, Traumatic (Phase 1/Phase 2)

Diabetes Mellitus, Type 2 (Phase 1)

Heart Failure (Phase 1)

Overview

Highest Phase: Phase 2
# of Trials: 18
# of Trial Organizations: 17

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

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