beta carotene (solatene) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Beta-carotene is found in many foods and is sold as a dietary supplement. Beta-carotene is a carotenoid, weak antioxidant; precursor of vitamin A, which is essential for vision and growth. Used to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (EPP). Has been used in high-dose antioxidant supplements containing ascorbic acid and vitamin E with zinc in high-risk patients with age-related macular degeneration. Beta-carotene is also used to decrease asthma symptoms caused by exercise; to prevent certain cancers, heart disease, cataracts; and to treat AIDS, alcoholism, Alzheimer’s disease, depression, epilepsy, headache, heartburn, high blood pressure, infertility, Parkinson’s disease, rheumatoid arthritis, schizophrenia, and skin disorders including psoriasis and vitiligo.   NCATS

Chemistry

  • SMILES: CC(\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C
  • InChIKey: OENHQHLEOONYIE-JLTXGRSLSA-N
  • Mol. Mass: 536.8726
  • ALogP: 12.61
  • ChEMBL Molecule:
    beta carotene  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No

Alternative names

b-carotene | betacarotene | beta carotene | beta-carotene | betavit | eldon | gerard | golden rose | lucaratin | lumitene | nature's plus | optimum | optimun | provatene | solatene

Organizations (62)

Research & Development (61)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (34)

Approved Indications (1)


 

Protoporphyria, Erythropoietic (approved 1975)

Experimental Indications - Clinical Trial Phases 1-4 (33)


 

Arterial Occlusive Diseases (Phase 3)

Cardiovascular Diseases (Phase 2)

Cataract (Phase 3)

Coronary Artery Disease (Phase 2)

Coronary Disease (Phase 2)

Crohn Disease (Phase 3)

Dermatology (Phase 1)

Diabetes Mellitus (Phase 3)

Enterocolitis, Necrotizing (Phase 4)

Graves Ophthalmopathy (Phase 2/Phase 3)

Head and Neck Neoplasms (Phase 3)

Hearing Loss, Noise-Induced (Phase 2)

Heart Diseases (Phase 3)

HIV Infections (Phase 3)

Hyaline Membrane Disease (Phase 4)

Infectious Disease Transmission, Vertical (Phase 3)

Infertility, Male (Phase 2)

Lung Neoplasms (Phase 4)

Macular Degeneration (Phase 3)

Myocardial Infarction (Phase 2)

Myocardial Ischemia (Phase 2)

Neoplasms (Phase 3)

Neuroblastoma ()

Oral Submucous Fibrosis (Phase 3)

Pancreatitis (Phase 2/Phase 3)

Pancreatitis, Chronic (Phase 3)

Pregnancy Complications (Phase 3)

Premature Birth (Phase 4)

Psoriasis (Phase 3)

Retinitis Pigmentosa (Phase 3)

Vascular Diseases (Phase 3)

Vitamin A (Phase 3)

Vitamin A Deficiency (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 31
  • # of Trial Organizations: 61

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue