Active Ingredient History
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication primarily used to treat severe acne. It is also used to prevent certain skin cancers, and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Acne Vulgaris (approved 1982)
Acneiform Eruptions (Phase 4)
Alzheimer Disease (Phase 1/Phase 2)
Anus Neoplasms (Phase 1)
Astrocytoma (Phase 1)
Brain Neoplasms (Phase 3)
Breast Neoplasms (Phase 3)
Burkitt Lymphoma (Phase 1)
Carcinoma, Renal Cell (Phase 1/Phase 2)
Central Nervous System Neoplasms (Phase 3)
Chromosome Aberrations (Phase 2)
COVID-19 (Phase 4)
COVID-19 Vaccines (Phase 1/Phase 2)
Cytochrome P-450 CYP2D6 (Phase 4)
Dermatitis, Phototoxic (Phase 2)
Dermatitis, Seborrheic (Phase 4)
Epidermolysis Bullosa (Phase 1)
Esophageal Neoplasms (Phase 2)
Ganglioneuroblastoma (Phase 3)
Glioblastoma (Phase 2)
Glioma (Phase 1/Phase 2)
Gliosarcoma (Phase 1)
Head and Neck Neoplasms (Phase 3)
Healthy Volunteers (Phase 1)
Hematologic Neoplasms (Phase 2)
HIV Infections (Phase 3)
Hodgkin Disease (Phase 1)
Ichthyosis (Phase 3)
Infertility, Male (Phase 2)
Intraocular Lymphoma (Phase 1)
Keratosis, Actinic (Phase 2)
Kidney Neoplasms (Phase 3)
Klinefelter Syndrome (Phase 2)
Leukemia (Phase 2)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1)
Leukemia-Lymphoma, Adult T-Cell (Phase 1)
Leukemia, Myeloid, Acute (Phase 1)
Leukemia, Myeloid, Chronic-Phase (Phase 1)
Leukemia, Myelomonocytic, Juvenile (Phase 2)
Leukoplakia, Oral (Phase 1)
Lung Neoplasms (Phase 3)
Lymphoma (Phase 1)
Lymphoma, B-Cell, Marginal Zone (Phase 1)
Lymphoma, Follicular (Phase 1)
Lymphoma, Large B-Cell, Diffuse (Phase 1)
Lymphoma, Large-Cell, Anaplastic (Phase 1)
Lymphoma, Large-Cell, Immunoblastic (Phase 1)
Lymphoma, Mantle-Cell (Phase 1)
Lymphoma, Non-Hodgkin (Phase 1)
Lymphoma, T-Cell (Phase 2)
Lymphomatoid Granulomatosis (Phase 1)
Medulloblastoma (Phase 3)
Melanoma (Phase 2)
Multiple Myeloma (Phase 2)
Mycosis Fungoides (Phase 2)
Myelodysplastic Syndromes (Phase 1/Phase 2)
Myeloproliferative Disorders (Phase 1/Phase 2)
Neoplasms (Phase 1)
Neoplasms, Second Primary (Phase 4)
Nerve Sheath Neoplasms (Phase 2)
Neuroblastoma (Phase 3)
Neuroectodermal Tumors (Phase 1)
Oligodendroglioma (Phase 1)
Penile Neoplasms (Phase 2)
Pharmacokinetics (Phase 4)
Prostatic Neoplasms (Phase 2)
Quality of Life (Phase 4)
Rhabdoid Tumor (Phase 1)
Rosacea (Phase 3)
Sezary Syndrome (Phase 1)
Squamous Cell Carcinoma of Head and Neck (Phase 3)
Thrombocytopenia (Phase 1/Phase 2)
Tinea (Phase 2)
Tuberculosis (Phase 2)
Tumor Suppressor Protein p53 (Phase 2)
Uterine Cervical Dysplasia (Phase 3)
Uterine Cervical Neoplasms (Phase 2)
Vitreoretinopathy, Proliferative (Phase 4)
Waldenstrom Macroglobulinemia (Phase 1)
Warts (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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