beraprost Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Beraprost is a pharmaceutical drug used in several Asian countries, including Japan and South Korea, as a vasodilator and antiplatelet agent. It is classified as a prostacyclin analog.   Wikipedia

Chemistry

  • SMILES: CC#CCC(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2Oc3c(CCCC(=O)O)cccc3[C@H]12
  • InChIKey: CTPOHARTNNSRSR-APJZLKAGSA-N
  • Mol. Mass: 398.5
  • ALogP: 3.29
  • ChEMBL Molecules:
    beraprost  
    esuberaprost  
    beraprost sodium  
More Chemistry

Pharmacology

Alternative names

1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-, monosodium salt | 4-(1,2,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyloct-6-yne-1-enyl)-5-cyclopenta(b)benzofuranyl)butyrate | aps-314d | beraprost | beraprost sodium | mdl-201129 | mdl-201229 | ml-1129 | ml-1229 | procylin | prostaglandin i2 analogue | trk 100 | trk-100 | trk-100stp

Organizations (9)

Research & Development (9)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (11)

Approved Indications (1)


 

Hypertension, Pulmonary

Experimental Indications - Clinical Trial Phases 1-4 (11)


 

Diabetes Mellitus, Type 2 (Phase 4)

Essential Hypertension (Early Phase 1)

Healthy Volunteers (Phase 1)

Hypertension, Pulmonary (Phase 4)

Kidney Diseases (Phase 3)

Kidney Failure, Chronic (Phase 2/Phase 3)

Kidney Glomerulus (Phase 2/Phase 3)

Nephrosclerosis (Phase 2/Phase 3)

Pharmacokinetics (Phase 1)

Pulmonary Arterial Hypertension (Phase 3)

Renal Insufficiency, Chronic (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 19
  • # of Trial Organizations: 9

Trials by Phase

Trial Phase Start Date Organizations Indications

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