Active Ingredient History
Tolerogenic dendritic cells are heterogenous pool of dendritic cells with immuno-suppressive properties, priming immune system into tolerogenic state against various antigens. These tolerogenic effects are mostly mediated through regulation of T cells such as inducing T cell anergy, T cell apoptosis and induction of Tregs. Tol-DCs also affect local micro-environment toward tolerogenic state by producing anti-inflammatory cytokines. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Arthritis (Phase 1)
Arthritis, Rheumatoid (Phase 1)
Autoimmune Diseases (Phase 1)
Connective Tissue Diseases (Phase 1)
Diabetes Mellitus (Phase 1/Phase 2)
Immune System Diseases (Phase 1)
Joint Diseases (Phase 1)
Musculoskeletal Diseases (Phase 1)
Myocardial Infarction (Phase 1/Phase 2)
Rheumatic Diseases (Phase 1)
Trial | Phase | Start Date | Organizations | Indications |
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