Active Ingredient History

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Trichloroacetic acid (TCA; TCAA) is a chemical used in skin peel formulations. It is more frequently used for lighter skin and is less used on darker skin because of the higher risks of scarring, as well as post-peel dyschromias. Low concentrations, 10-35% is preferred for skin peel formulations so that it only reaches the upper papillary dermis. Topical TCA is an efficacious treatment of internal anal high-grade squamous intraepithelial lesions (HSIL). Advantages of TCA for this recurrent disease process include low cost, no requirement for special equipment beyond that for high-resolution anoscopy, and painless application procedure.   NCATS

  • SMILES: OC(=O)C(Cl)(Cl)Cl
  • InChIKey: YNJBWRMUSHSURL-UHFFFAOYSA-N
  • Mol. Mass: 163.387
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
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