Active Ingredient History

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Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. Silibinin is used in pure forms as a medication, and more frequently as an active ingredient in milk thistle–derived herbal supplements.   Wikipedia

  • SMILES: COc1cc(ccc1O)C2Oc3cc(ccc3OC2CO)C4Oc5cc(O)cc(O)c5C(=O)C4O
  • InChIKey: SEBFKMXJBCUCAI-UHFFFAOYSA-N
  • Mol. Mass: 482.44
  • ALogP: 2.36
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
2,3-dehydrosilybin | alepa-forte | ardeyhepan | cdp | cefasilymarin | durasilymarin | hepabesch | hepa-loges | hepa-merz sil | hepar-pasc | heparsyx | hepatos | heplant | lagosa | legalon forte | silibin | silibinin | silibrin | silybin | silybinin

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