API | aceclofenac

aceclofenac Report issue

Small molecule Experimental

AACT ChEMBL Drug Central PubChem

Active Ingredient History

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Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. ^Wikipedia

Chemistry

SMILES: OC(=O)Cc1c(c2ccccc2)c(nn1c3ccccc3)c4ccccc4
InChIKey: LZRDDINFIHUVCX-UHFFFAOYSA-N
Mol. Mass: 354.41
ALogP: 4.83 Partition coefficient
ChEMBL Molecule:
isofezolac

More Chemistry

Pharmacology

Mechanism of Action:
- Prostaglandin G/H synthase 2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

fed | isofezolac | nvp-1203 | sofenac

Organizations (16)

Research & Development (16)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (10)

Approved Indications (1)

Pain

Experimental Indications - Clinical Trial Phases 1-4 (9)

Acute Pain (Phase 3)

Analgesia ()

Anti-Ulcer Agents (Phase 1)

Arthritis, Rheumatoid (Phase 4)

Depressive Disorder, Major (Phase 2)

Drug Interactions (Phase 1)

Healthy Volunteers (Phase 1)

Stress Disorders, Post-Traumatic (Phase 2)

Therapeutic Equivalency (Phase 1)

Overview

Highest Phase: Phase 4
# of Trials: 15
# of Trial Organizations: 16

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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