API | linzagolix

linzagolix Report issue

Small molecule Experimental

Active Ingredient History

NOW

Linzagolix, sold under the brand name Yselty, is a medication used in the treatment of uterine fibroids. Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist developed by Kissei Pharmaceutical and ObsEva. ^Wikipedia

Chemistry

SMILES: COc1cc(F)c(-n2c(=O)[nH]c3csc(C(=O)O)c3c2=O)cc1OCc1c(OC)ccc(F)c1F
InChIKey: BMAAMIIYNNPHAB-UHFFFAOYSA-N
Mol. Mass: 508.43
ALogP: 3.45 Partition coefficient
ChEMBL Molecule:
linzagolix

More Chemistry

Pharmacology

Mechanisms of Action:
- Gonadotropin-releasing hormone receptor (Homo sapiens) ^UniProt
- Gonadotropin-releasing hormone receptor (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

Organizations (4)

Research & Development (4)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Endometriosis (Phase 3)

Healthy Volunteers (Phase 1)

Kidney Failure, Chronic (Phase 1)

Leiomyoma (Phase 3)

Liver Diseases (Phase 1)

Menorrhagia (Phase 3)

Reproductive Techniques, Assisted (Phase 2)

Overview

Highest Phase: Phase 3
# of Trials: 9
# of Trial Organizations: 4

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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