API | napabucasin

napabucasin Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Chemistry

SMILES: CC(=O)c1oc2C(=O)c3ccccc3C(=O)c2c1
InChIKey: DPHUWDIXHNQOSY-UHFFFAOYSA-N
Mol. Mass: 240.21
ALogP: 2.26 Partition coefficient
ChEMBL Molecule:
napabucasin

More Chemistry

Pharmacology

Mechanism of Action:
- Signal transducer and activator of transcription 3 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

2-acetylfuranonaphthoquinone | 2-acetyl furanonaphthoquinone | 2-acetyl furanonapthoquinone | bbi608 | bbi-608 | fnq cpd | napabucasin

Organizations (9)

Research & Development (9)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (15)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (15)

Carcinoma, Hepatocellular (Phase 1/Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 3)

Carcinoma, Pancreatic Ductal (Phase 3)

Colorectal Neoplasms (Phase 3)

Drug Interactions (Phase 1)

Esophageal Neoplasms (Phase 3)

Glioblastoma (Phase 1/Phase 2)

Healthy Volunteers (Phase 1)

Hematologic Neoplasms (Phase 1)

Intestinal Neoplasms (Phase 1/Phase 2)

Mesothelioma, Malignant (Phase 1/Phase 2)

Neoplasms (Phase 1/Phase 2)

Pancreatic Neoplasms (Phase 3)

Pharmacokinetics (Phase 1)

Stomach Neoplasms (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 26
# of Trial Organizations: 9

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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