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Small molecule Experimental

AACT PubChem

Active Ingredient History

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Chemistry

SMILES: Cc1nc2cc(C(=O)N(C)C)cc(O[C@H]3CCOc4cc(F)cc(F)c43)c2[nH]1
InChIKey: CLIQCDHNPDMGSL-HNNXBMFYSA-N
Mol. Mass: 387.39
ALogP: 3.75 Partition coefficient
ChEMBL Molecule:
tegoprazan

More Chemistry

Pharmacology

Mechanisms of Action:
- Potassium-transporting ATPase alpha chain 1 (Homo sapiens) ^UniProt
- Potassium-transporting ATPase subunit beta (Homo sapiens) ^UniProt
- Solute carrier organic anion transporter family member 4A1 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

cj-12420

Organizations (25)

Research & Development (25)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (18)

Approved Indications (1)

Gastroesophageal Reflux

Experimental Indications - Clinical Trial Phases 1-4 (18)

Acute Coronary Syndrome (Phase 3)

Coronary Artery Disease (Phase 3)

Drug Interactions (Phase 1)

Drug Therapy (Phase 4)

Duodenal Ulcer (Phase 3)

Dyspepsia (Phase 4)

Esophagitis (Phase 3)

Gastroesophageal Reflux (Phase 4)

Healthy Volunteers (Phase 1)

Helicobacter pylori (Phase 4)

Liver Diseases (Phase 1)

Myocardial Infarction (Phase 3)

Peptic Ulcer (Phase 3)

Percutaneous Coronary Intervention (Phase 3)

Pharmacokinetics (Phase 1)

Proton Pump Inhibitors (Phase 4)

Stomach Ulcer (Phase 3)

Overview

Highest Phase: Phase 4
# of Trials: 53
# of Trial Organizations: 25

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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