Active Ingredient History
Propofol is the active component of an intravenous anesthetic formulation used for induction and maintenance of general anesthesia. It is chemically termed 2,6-diisopropylphenol. The formulation was approved under the brand name Diprivan. Numerous generic versions have since been released. Intravenous administration is used to induce unconsciousness after which anesthesia may be maintained using a combination of medications. It is manufactured as part of a sterile injectable emulsion formulation using soybean oil and lecithin, giving it a white milky coloration. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Pain (approved 1989)
Abdominal Neoplasms (Phase 4)
Ablation Techniques (Phase 4)
Abortion, Induced (Phase 4)
Abscess (Phase 3)
Acne Vulgaris (Phase 4)
Acute Kidney Injury (Phase 4)
Acute Pain (Phase 4)
Aged (Phase 4)
Airway Extubation (Phase 4)
Alcohol Amnestic Disorder (Phase 4)
Alcohol Drinking (Phase 4)
Alcoholism (Phase 4)
Allergy and Immunology (Phase 3)
Alzheimer Disease (Phase 4)
Ambulatory Surgical Procedures (Phase 4)
Amnesia (Phase 1)
Analgesia (Phase 4)
Analgesia, Patient-Controlled (Phase 4)
Analgesics, Opioid (Phase 4)
Anesthesia (Phase 4)
Anesthesia, Conduction (Phase 4)
Anesthesia, Endotracheal (Phase 4)
Anesthesia, Epidural (Phase 4)
Anesthesia, General (Phase 4)
Anesthesia, Inhalation (Phase 4)
Anesthesia, Intravenous (Phase 4)
Anesthesia, Local (Phase 4)
Anesthesia Recovery Period (Phase 4)
Anesthesia, Spinal (Phase 4)
Anesthetics (Phase 4)
Anesthetics, General (Phase 3)
Anesthetics, Intravenous (Phase 4)
Aneurysm (Phase 4)
Anti-Anxiety Agents (Phase 4)
Anxiety (Phase 4)
Aortic Diseases (Phase 4)
Aortic Valve Insufficiency (Phase 3)
Appendicitis (Phase 3)
Arteriovenous Fistula (Phase 4)
Arthritis (Phase 4)
Arthroplasty (Phase 4)
Arthroplasty, Replacement, Hip (Phase 4)
Arthroplasty, Replacement, Knee (Phase 4)
Asthma (Phase 4)
Athletic Injuries (Phase 4)
Atrial Fibrillation (Phase 4)
Atrial Flutter (Phase 4)
Auditory Diseases, Central (Early Phase 1)
Automobile Driving (Phase 4)
Back Pain (Phase 3)
Bariatrics (Phase 4)
Bariatric Surgery (Phase 4)
Behavior (Phase 4)
Benzodiazepines (Phase 4)
Biliary Atresia (Phase 4)
Bone Marrow Diseases (Phase 3)
Brachial Plexus Block (Phase 4)
Brain Diseases (Phase 4)
Brain Injuries (Phase 4)
Brain Injuries, Traumatic (Phase 4)
Brain Neoplasms (Phase 4)
Breast Diseases (Phase 3)
Breast Neoplasms (Phase 4)
Bronchial Diseases (Phase 4)
Bronchial Spasm (Phase 4)
Bronchiectasis (Phase 4)
Bronchoscopy (Phase 4)
Cannabis (Phase 4)
Carcinoma (Phase 4)
Carcinoma, Hepatocellular (Phase 4)
Carcinoma, Non-Small-Cell Lung (Phase 3)
Cardiovascular Diseases (Phase 4)
Carotid Stenosis (Phase 4)
Cataract (Phase 4)
Cerebral Arterial Diseases (Phase 3)
Cerebral Palsy (Phase 4)
Cerebrovascular Circulation (Phase 4)
Cesarean Section (Phase 4)
Child (Phase 4)
Cholangitis (Phase 2)
Cholecystectomy, Laparoscopic (Phase 4)
Choledochal Cyst (Phase 4)
Chronic Pain (Phase 4)
Cognition (Phase 4)
Cognition Disorders (Phase 4)
Cognitive Aging (Phase 4)
Cognitive Dysfunction (Phase 4)
Colonic Diseases (Phase 3)
Colonic Neoplasms (Phase 4)
Colonoscopy (Phase 4)
Colorectal Neoplasms (Phase 4)
Confusion (Phase 4)
Congenital Abnormalities (Phase 4)
Consciousness (Phase 4)
Consciousness Disorders (Phase 4)
Conscious Sedation (Phase 4)
Coronary Artery Bypass (Phase 4)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 4)
COVID-19 (Phase 4)
Craniotomy (Phase 4)
Critical Illness (Phase 4)
Cryptorchidism (Phase 4)
Deep Sedation (Phase 4)
Delayed Emergence from Anesthesia (Phase 4)
Delirium (Phase 4)
Dementia (Phase 4)
Depression (Phase 4)
Depressive Disorder (Early Phase 1)
Depressive Disorder, Major (Phase 1)
Depressive Disorder, Treatment-Resistant (Phase 4)
Desflurane (Phase 4)
Dexmedetomidine (Phase 4)
Digestive System Diseases (Phase 4)
Disease Progression (Phase 4)
DNA Damage (Phase 4)
Drug Interactions (Phase 4)
Drug Misuse (Phase 4)
Drugs, Investigational (Phase 4)
Dyssomnias (Phase 1)
Eating (Phase 4)
Electric Countershock (Phase 3)
Electroconvulsive Therapy (Phase 4)
Electroencephalography (Phase 4)
Emergence Delirium (Phase 4)
Emergencies (Phase 4)
Endoscopy (Phase 4)
Endoscopy, Gastrointestinal (Phase 4)
End Stage Liver Disease (Phase 4)
Energy Metabolism (Phase 4)
Epigenomics (Phase 4)
Epilepsy (Phase 4)
Epiretinal Membrane (Phase 4)
Esophageal and Gastric Varices (Phase 4)
Esophageal Neoplasms (Phase 3)
Etomidate (Phase 4)
Evoked Potentials, Motor (Phase 4)
Fatigue (Phase 4)
Femoral Neck Fractures (Phase 4)
Femur Head Necrosis (Early Phase 1)
Fibrosis (Phase 4)
Fracture Fixation (Phase 3)
Fractures, Bone (Phase 4)
Gallbladder Diseases (Phase 4)
Gallstones (Phase 4)
Gastrectomy (Phase 4)
Gastric Bypass (Phase 4)
General Surgery (Phase 4)
Genital Diseases, Female (Phase 4)
Geriatrics (Phase 4)
Glycogen Synthase Kinase 3 (Phase 4)
Growth and Development (Phase 4)
Gynecology (Phase 4)
Headache (Phase 4)
Headache Disorders (Phase 2)
Headache Disorders, Secondary (Phase 2)
Health (Phase 4)
Healthy Volunteers (Phase 4)
Heart Arrest (Phase 4)
Heart Defects, Congenital (Phase 4)
Heart Diseases (Phase 4)
Heart Septal Defects, Atrial (Phase 4)
Heart Valve Diseases (Phase 4)
Hematoma, Subdural, Acute (Phase 4)
Hemodialysis, Home (Phase 4)
Hemodynamics (Phase 4)
Hemorrhage (Phase 2)
Hemostasis, Endoscopic (Phase 4)
Hepatectomy (Phase 3)
Hepatic Encephalopathy (Phase 4)
Hernia (Phase 4)
Hernia, Inguinal (Phase 4)
Hip Fractures (Phase 4)
Hospices (Phase 4)
Hydrocephalus (Phase 4)
Hyperalgesia (Phase 4)
Hypertension (Phase 3)
Hypertension, Pulmonary (Phase 4)
Hypnosis (Phase 4)
Hypnotics and Sedatives (Phase 4)
Hypotension (Phase 4)
Hypothermia (Phase 4)
Hypoxia (Phase 4)
Hypoxia, Brain (Phase 4)
Hysterectomy (Phase 4)
Hysteroscopy (Phase 4)
Infant, Premature (Phase 1)
Infections (Phase 4)
Infertility (Phase 4)
Inflammation (Phase 4)
Inflammatory Bowel Diseases (Phase 4)
Infusions, Intravenous (Phase 4)
Inhalation (Phase 4)
Intensive Care Units (Phase 4)
Intestinal Neoplasms (Phase 4)
Intestinal Polyps (Phase 4)
Intestinal Pseudo-Obstruction (Phase 4)
Intra-Abdominal Hypertension (Phase 4)
Intracranial Aneurysm (Phase 3)
Intracranial Pressure (Phase 1/Phase 2)
Intraocular Pressure (Phase 4)
Intraoperative Awareness (Phase 4)
Intubation (Phase 4)
Intubation, Intratracheal (Phase 4)
Irritable Bowel Syndrome (Phase 4)
Joint Dislocations (Phase 4)
Ketamine (Phase 4)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 4)
Kidney Neoplasms (Phase 4)
Kidney Transplantation (Phase 3)
Lactation Disorders (Phase 1)
Laparoscopy (Phase 4)
Laryngeal Masks (Phase 4)
Leukemia (Phase 2/Phase 3)
Lidocaine (Phase 4)
Liver Cirrhosis (Phase 3)
Liver Diseases (Phase 4)
Liver Neoplasms (Phase 4)
Lumbar Vertebrae (Phase 3)
Lung (Phase 4)
Lung Diseases (Phase 4)
Lung Neoplasms (Phase 4)
Lung Transplantation (Phase 4)
Lymphoma (Phase 2/Phase 3)
Magnesium (Phase 2/Phase 3)
Magnetic Resonance Imaging (Phase 4)
Magnetic Resonance Spectroscopy (Phase 4)
Mastectomy (Phase 4)
Mastectomy, Radical (Phase 1/Phase 2)
Melanoma (Phase 4)
Memory Disorders (Phase 4)
Mental Disorders (Phase 4)
Microcirculation (Phase 4)
Migraine Disorders (Phase 2/Phase 3)
Mitral Valve Insufficiency (Phase 4)
Morphine (Phase 2)
Muscle Relaxants, Central (Phase 4)
Muscle Relaxation (Phase 3)
Muscular Dystrophies (Phase 4)
Musculoskeletal Diseases (Phase 4)
Myocardial Reperfusion Injury (Phase 1/Phase 2)
Myocardium (Phase 2/Phase 3)
Myoclonus (Phase 4)
Nausea (Phase 4)
Neonatology (Phase 2)
Neoplasm Metastasis (Phase 4)
Neoplasms (Phase 4)
Neoplastic Cells, Circulating (Phase 2)
Nerve Block (Phase 4)
Neurocognitive Disorders (Phase 4)
Neurofibromatoses (Phase 4)
Neuromuscular Blockade (Phase 4)
Neuromuscular Junction Diseases (Phase 3)
Neurosurgery (Phase 3)
Nociceptive Pain (Phase 4)
Obesity (Phase 4)
Obesity, Morbid (Phase 4)
Oocyte Retrieval (Phase 4)
Orthopedic Procedures (Phase 4)
Osteoarthritis (Phase 4)
Osteoarthritis, Hip (Phase 4)
Osteoarthritis, Knee (Phase 4)
Ovarian Neoplasms (Phase 4)
Oxidative Stress (Phase 4)
Pain (Phase 4)
Pain, Intractable (Phase 4)
Pain, Postoperative (Phase 4)
Palonosetron (Phase 4)
Pancreatic Neoplasms (Phase 3)
Pancreatitis (Phase 2)
Parkinson Disease (Phase 4)
Patient Satisfaction (Phase 4)
Pediatrics (Phase 4)
Perfusion (Phase 2/Phase 3)
Perioperative Care (Phase 4)
Peritonitis (Phase 4)
Personal Satisfaction (Phase 4)
Pharmacokinetics (Phase 4)
Pituitary Neoplasms (Phase 4)
Plasma (Phase 4)
Pneumonectomy (Phase 4)
Pneumonia (Phase 4)
Pneumonia, Aspiration (Phase 4)
Polymorphism, Genetic (Phase 4)
Polyps (Phase 4)
Postoperative Cognitive Complications (Phase 4)
Postoperative Complications (Phase 4)
Postoperative Nausea and Vomiting (Phase 4)
Pregnancy (Phase 4)
Premedication (Phase 2/Phase 3)
Propofol (Phase 4)
Prostatic Neoplasms (Phase 4)
Prostheses and Implants (Phase 2)
Pruritus (Early Phase 1)
Psychological Distress (Phase 2/Phase 3)
Psychotropic Drugs (Phase 4)
Pulmonary Atelectasis (Phase 4)
Quality of Life (Phase 3)
Radiculopathy (Phase 3)
Rectal Neoplasms (Phase 4)
Remifentanil (Phase 2)
Renal Insufficiency (Phase 1)
Reperfusion Injury (Phase 4)
Respiration, Artificial (Phase 4)
Respiratory Distress Syndrome (Phase 4)
Respiratory Insufficiency (Phase 4)
Respiratory Tract Infections (Phase 4)
Retinal Detachment (Phase 4)
Retinal Diseases (Phase 4)
Retinal Perforations (Phase 4)
Rotator Cuff Injuries (Phase 4)
Safety (Phase 4)
Schizophrenia (Phase 4)
Sclerosis (Phase 4)
Scoliosis (Phase 4)
Sepsis (Phase 4)
Severe Acute Respiratory Syndrome (Phase 4)
Sevoflurane (Phase 4)
Shock (Phase 4)
Shock, Septic (Phase 3)
Shoulder Dislocation (Phase 4)
Shoulder Pain (Phase 4)
Sinusitis (Phase 4)
Sleep (Phase 4)
Sleep Apnea, Obstructive (Phase 4)
Sleep Apnea Syndromes (Phase 4)
Sleep Disorders, Circadian Rhythm (Phase 3)
Sleep Quality (Phase 4)
Sleep Wake Disorders (Phase 4)
Spinal Fusion (Phase 3)
Spinal Injuries (Phase 4)
Spinal Puncture (Phase 3)
Spinal Stenosis (Early Phase 1)
Status Epilepticus (Phase 3)
Stomach Neoplasms (Phase 4)
Stomach Ulcer (Phase 4)
Strabismus (Phase 2)
Stroke (Phase 4)
Subarachnoid Hemorrhage (Phase 4)
Supratentorial Neoplasms (Phase 4)
Surgical Oncology (Phase 4)
Surgical Procedures, Operative (Phase 4)
Survival (Phase 4)
Thoracic Diseases (Phase 4)
Thoracic Surgery (Phase 4)
Thyroid Gland (Phase 4)
Tonsillitis (Phase 2)
Tracheostomy (Phase 4)
Transcatheter Aortic Valve Replacement (Phase 4)
Tuberculosis (Phase 2)
Unconsciousness (Phase 4)
Urinary Bladder Neoplasms (Phase 4)
Vascular Diseases (Phase 4)
Vascular Surgical Procedures (Phase 4)
Vasoconstrictor Agents (Phase 4)
Venous Cutdown (Phase 4)
Ventilators, Mechanical (Phase 4)
Vision, Ocular (Phase 4)
Vital Signs (Phase 1)
Vitrectomy (Phase 4)
Vitreous Detachment (Phase 4)
Vitreous Hemorrhage (Phase 4)
Vomiting (Phase 4)
Wounds and Injuries (Phase 2/Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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