Active Ingredient History
Mogamulizumab, sold under the brand name Poteligeo, is a humanized, afucosylated monoclonal antibody targeting CC chemokine receptor 4 (CCR4). The U.S. Food and Drug Administration (FDA) approved it in August 2018 for treatment of relapsed or refractory mycosis fungoides and Sézary disease. It was approved in Japan in 2012, for the treatment of relapsed or refractory CCR4+ adult T-cell leukemia/lymphoma (ATCLL) and in 2014, for relapsed or refractory CCR4+ cutaneous T cell lymphoma (CTCL). The latter approval was based on study with 28 subjects. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Asthma (Phase 1)
Carcinoma (Phase 1/Phase 2)
Carcinoma, Hepatocellular (Phase 1/Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 1)
Esophageal Neoplasms (Phase 1)
Kidney Neoplasms (Phase 1)
Leukemia-Lymphoma, Adult T-Cell (Phase 2)
Lung Neoplasms (Phase 1)
Lymphoma, B-Cell (Phase 1/Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 1/Phase 2)
Lymphoma, Non-Hodgkin (Phase 2)
Lymphoma, T-Cell (Phase 2)
Lymphoma, T-Cell, Cutaneous (Phase 3)
Lymphoma, T-Cell, Peripheral (Phase 2)
Mouth Neoplasms (Phase 1)
Mycosis Fungoides (Phase 2)
Neoplasms (Phase 1/Phase 2)
Paraparesis, Tropical Spastic (Phase 3)
Sezary Syndrome (Phase 2)
Stomach Neoplasms (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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