API | becatecarin

becatecarin Report issue

Small molecule Experimental

AACT ChEMBL MeSH PubChem

Active Ingredient History

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Chemistry

SMILES: CCN(CC)CCN1C(=O)c2c(C1=O)c3c4cccc(Cl)c4n([C@@H]5O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)c3c6[nH]c7c(Cl)cccc7c26
InChIKey: JSKFWUPVIZYJMR-UDOAKELVSA-N
Mol. Mass: 669.56
ALogP: 4.3 Partition coefficient
ChEMBL Molecule:
becatecarin

More Chemistry

Pharmacology

Mechanisms of Action:
- DNA topoisomerase 1 (Homo sapiens) ^UniProt
- DNA topoisomerase 2-alpha (Homo sapiens) ^UniProt
- DNA topoisomerase 2-beta (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

becatecarin | becatecarin hydrochloride | becatecarin tartrate | bm-27557-14 | bms 181176 | bms-181176 | bms 181176-1 | bms-181176-1 | bms 181176-14 | bms-181176-14 | bmy 27557 | bmy-27557 | bmy 27557-1 | bmy-27557-1 | bmy 27557-14 | deae-rbm | diethylaminoethyl-rebeccamycin | nsc 655649 | nsc-655649 | nsc d640199 | nsc-d640199 | rebeccamycin, diethylaminoethyl- | xl 119 | xl-119 | xl119 compound

Organizations (10)

Research & Development (10)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (25)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (25)

Anemia, Refractory (Phase 1)

Bile Duct Neoplasms (Phase 2)

Biliary Tract Neoplasms (Phase 3)

Brain Neoplasms (Phase 2)

Breast Neoplasms (Phase 2)

Breast Neoplasms, Male (Phase 2)

Colorectal Neoplasms (Phase 2)

Gallbladder Neoplasms (Phase 2)

Intestinal Neoplasms (Phase 1)

Kidney Neoplasms (Phase 2)

Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1)

Leukemia, Myeloid, Acute (Phase 1)

Leukemia, Myeloid, Chronic-Phase (Phase 1)

Leukemia, Myelomonocytic, Chronic (Phase 1)

Liver Neoplasms (Phase 2)

Lung Neoplasms (Phase 2)

Lymphoma (Phase 2)

Myelodysplastic Syndromes (Phase 1)

Neoplasms (Phase 2)

Neuroblastoma (Phase 2)

Ovarian Neoplasms (Phase 2)

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Phase 1)

Retinoblastoma (Phase 2)

Sarcoma (Phase 2)

Small Cell Lung Carcinoma (Phase 2)

Overview

Highest Phase: Phase 3
# of Trials: 13
# of Trial Organizations: 10

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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