Active Ingredient History

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Piroxicam is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It was originally brought to market by Pfizer under the tradename Feldene in 1980, became generic in 1992, and is marketed worldwide under many brandnames. Piroxicam works by reducing hormones that cause inflammation and pain in the body. Piroxicam is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis. The antiinflammatory effect of Piroxicam may result from the reversible inhibition of cyclooxygenase, causing the peripheral inhibition of prostaglandin synthesis. The prostaglandins are produced by an enzyme called Cox-1. Piroxicam blocks the Cox-1 enzyme, resulting into the disruption of production of prostaglandins. Piroxicam also inhibits the migration of leukocytes into sites of inflammation and prevents the formation of thromboxane A2, an aggregating agent, by the platelets. Piroxicam is used for treatment of osteoarthritis and rheumatoid arthritis.   NCATS

  • SMILES: CN1C(C(=O)NC2=CC=CC=N2)=C(O)C3=CC=CC=C3S1(=O)=O
  • InChIKey: QYSPLQLAKJAUJT-UHFFFAOYSA-N
  • Mol. Mass: 331.346
  • ALogP: 1.58
  • ChEMBL Molecules:
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Drug Pricing (per unit)

Australia

$0.0789 - $0.3963

United States

$0.0803 - $13.2173
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

4-hydroxy-2-methyl-n-(2-pyridyl)-2h-1,2-benzothiazin-3-caboxyamid-1,1-dioxid | brexicam | brexidol | brexin | cicladol | cp16171 | cp-16171 | feldene | feldene 20 | feldene p | flamatrol | kentene | larapam | piroflam 10 | piroflam 20 | piroxicam | piroxicam beta-cyclodextrin | piroxicam-beta-cyclodextrin | piroxicam-beta-cyclodextrin complex | piroxicam betadex | piroxicamum | pirozip 10 | pirozip 20 | pyroxycam

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