Active Ingredient History
Levalbuterol is the (R)-enantiomer of the drug substance racemic albuterol (salbutamol). Binding studies have demonstrated that (R)-albuterol binds to the beta2-adrenergic receptor with a high affinity, whereas (S)-albuterol binds with 100-fold less affinity than (R)-albuterol. Other evaluations have suggested that (R)-albuterol possesses the bronchodilatory, bronchoprotective, and ciliary-stimulatory properties of racemic albuterol, while (S)-albuterol does not contribute beneficially to the therapeutic effects of the racemate and was originally assumed to be inert. Xopenex (levalbuterol HCl) Inhalation Solution is indicated for the treatment or prevention of bronchospasm in adults, adolescents, and children 6 years of age and older with reversible obstructive airway disease. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Asthma (approved 1999)
Pulmonary Disease, Chronic Obstructive (approved 1999)
Airway Management (Phase 3)
Asthma (Phase 4)
Asthma, Exercise-Induced (Phase 3)
Bronchoconstriction (Phase 3)
Hyperkalemia (Phase 4)
Mucociliary Clearance (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Sepsis (Phase 4)
Shock (Phase 4)
Trial | Phase | Start Date | Organizations | Indications |
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