Active Ingredient History

Dihydro-alpha-ergocryptine is an ergot alkaloid that has an agonist activity on D2 dopaminergic receptors and a partial agonist activity on D1 receptors. It also demonstrated antagonistic activity towards alpha-adrenergic receptors. The drug was approved by FDA in combination with other alkaloids (dihydroergocornine, dihydroergocristine and dihydro-beta-ergocryptine mesylate salts) under the name Hydergine for the treatment of dimentia and cerebrovascular insufficiency.   NCATS

  • SMILES: CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C
  • Mol. Mass: 577.73
  • ALogP: 2.52
  • ChEMBL Molecules:
More Chemistry
dihydro-.alpha.-ergocryptine | dihydro-.alpha.-ergocryptine mesilate | dihydro-.alpha.-ergocryptine mesylate | dihydroergocriptine | dihydroergocryptine mesilate | dihydroergocryptine mesylate


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