epicatechin Report issue

Small molecule Experimental
AACT DrugBank Drug Central PubChem

Active Ingredient History

NOW
  • Now
Sinecatechins is a specific water extract of green tea leaves from Camellia sinensis that is the active ingredient in an ointment approved by the FDA in 2006 as a botanical drug to treat genital warts. Sinecatechins are mostly catechins, 55% of which is epigallocatechin gallate. It was the first botanical drug approved by the US FDA.   Wikipedia

Chemistry

  • SMILES: Oc1cc(O)c2c(c1)O[C@@H](c1ccc(O)c(O)c1)[C@@H](O)C2
  • InChIKey: PFTAWBLQPZVEMU-ZFWWWQNUSA-N
  • Mol. Mass: 290.27
  • ALogP: 1.55
  • ChEMBL Molecules:
    (+)-epicatechin  
    (-)-epicatechin  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Drug Pricing (per unit)

United States

$29.2703
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

catechin | catechin extracts | catechins | catechu | epicatechin | (-)-epicatechin | (+)-epicatechin | tea catechin extracts

Organizations (49)

Research & Development (49)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (20)

Approved Indications (1)


 

Diabetes Mellitus, Type 2

Experimental Indications - Clinical Trial Phases 1-4 (19)


 

Antioxidants ()

Dyspareunia (Phase 4)

Friedreich Ataxia (Phase 2)

General Surgery (Phase 1/Phase 2)

Hypertension (Phase 2)

Muscular Dystrophy, Duchenne (Phase 2)

Neoplasms (Phase 3)

Osteoarthritis (Phase 1)

Pain (Phase 4)

Postmenopause (Phase 4)

Prediabetic State (Phase 1)

Prostatic Neoplasms (Phase 2)

Pulmonary Arterial Hypertension (Phase 1)

Sexual Dysfunction, Physiological (Phase 4)

Sexual Dysfunctions, Psychological (Phase 4)

Sexual Health (Phase 4)

Vaginal Diseases (Phase 4)

Vasodilation (Early Phase 1)

Vulvodynia (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 39
  • # of Trial Organizations: 49

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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