sulfoxone (Diasone) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Sulfoxone is a water-soluble sulfone and is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. Sulfoxone under the brand name Diasone was used as an antileprosy drug, for treatment of dermatitis herpetiformis, and to treat pulmonary tuberculosis. Presently, usage of diasone has been discontinued.   NCATS

Chemistry

  • SMILES: OS(=O)CNc1ccc(cc1)S(=O)(=O)c2ccc(NCS(=O)O)cc2
  • InChIKey: NEDPPCHNEOMTJV-UHFFFAOYSA-N
  • Mol. Mass: 404.49
  • ALogP: 1.7
  • ChEMBL Molecules:
    sulfoxone  
    sulfoxone sodium  
More Chemistry

Pharmacology

Alternative names

aldapsone | aldesulfone | aldesulfone sodium | aldesulfon sodium | aldesulphone | diasone | diasone sodium | sodium aldesulphone | sodium sulfoxone | sulfoxone | sulfoxone, disodium salt | sulfoxone sodium

Organizations (2)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (3)

Approved Indications (3)


 

Dermatitis Herpetiformis (approved 1986)

Leprosy (approved 1986)

Tuberculosis, Pulmonary (approved 1986)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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